SCAF8

Description		SR-related CTD associated factor 8
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm MRNA Cleavage Factor Complex Nuclear Matrix
	Molecular Function	RNA Polymerase II Complex Binding Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding RNA Polymerase Core Enzyme Binding RNA Polymerase II C-terminal Domain Phosphoserine Binding
	Biological Process	Termination Of RNA Polymerase II Transcription Positive Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled
Pathways
Drugs
Diseases
GWAS		Asthma ( 32296059) Bisphosphonate-associated atypical femoral fracture ( 31006051) Colorectal or endometrial cancer ( 26621817) Daytime nap ( 33568662) Diabetic kidney disease ( 26305897) Estimated glomerular filtration rate ( 31152163) Lipoprotein (a) levels ( 26377243)
Interacting Genes		4 interacting genes: GIGYF1 GOLGA2 RNF10 TEX11
Entrez ID		22828
HPRD ID		11487
Ensembl ID		ENSG00000213079
Uniprot IDs		A0A0A0MT33 B7Z3A4 B7Z876 Q9UPN6
PDB IDs		2DIW 3D9I 3D9J 3D9K 3D9L 3D9M 3D9N 3D9O 3D9P
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Glycosylation Regulation Of Protein Glycosylation Importin-alpha Family Protein Binding Golgi Disassembly Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Postsynapse To Nucleus Signaling Pathway Negative Regulation Of Schwann Cell Proliferation Extrinsic Component Of Postsynaptic Density Membrane Gene Conversion Central Element Male Meiosis Chromosome Segregation Meiotic Gene Conversion Chiasma Assembly Golgi Cis Cisterna Golgi Ribbon Formation Asymmetric Cell Division Meiotic Chromosome Segregation Positive Regulation Of Glycoprotein Biosynthetic Process Meiotic Spindle Assembly Negative Regulation Of Glial Cell Proliferation Resolution Of Meiotic Recombination Intermediates Ectopic Germ Cell Programmed Cell Death Positive Regulation Of Glycoprotein Metabolic Process Meiotic Spindle Organization Positive Regulation Of Myelination Programmed Cell Death Involved In Cell Development Synaptonemal Complex Assembly Synaptonemal Complex Synaptonemal Complex Organization Reciprocal Meiotic Recombination Negative Regulation Of Protein Binding Microtubule Nucleation
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