FGF9

Gene Name		fibroblast growth factor 9
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Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Fibroblast Growth Factor Receptor Binding Growth Factor Activity Heparin Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Angiogenesis Osteoblast Differentiation Positive Regulation Of Mesenchymal Cell Proliferation Chondrocyte Differentiation Protein Import Into Nucleus Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Proliferation Insulin Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Male Gonad Development Positive Regulation Of Gene Expression Substantia Nigra Development Negative Regulation Of Wnt Signaling Pathway Male Sex Determination Embryonic Limb Morphogenesis Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Activin Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Inner Ear Morphogenesis Positive Regulation Of MAPK Cascade Innate Immune Response Positive Regulation Of Smoothened Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Regulation Of Timing Of Cell Differentiation Embryonic Digestive Tract Development Embryonic Skeletal System Development Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Cell Division Positive Regulation Of Cardiac Muscle Cell Proliferation Lung-associated Mesenchyme Development Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Signaling by the B Cell Receptor (BCR) Phospholipase C-mediated cascade Signaling by FGFR in disease SHC-mediated cascade Signaling by EGFRvIII in Cancer Signaling by SCF-KIT Signaling by FGFR2 mutants DAP12 signaling Downstream signaling events of B Cell Receptor (BCR) PI3K/AKT activation PI-3K cascade Signaling by activated point mutants of FGFR1 Signaling by FGFR1 mutants PI3K Cascade Negative regulation of FGFR signaling Signaling by PDGF DAP12 interactions GAB1 signalosome Signaling by ERBB4 Role of LAT2/NTAL/LAB on calcium mobilization Constitutive PI3K/AKT Signaling in Cancer Activated point mutants of FGFR2 PI3K events in ERBB4 signaling Signaling by ERBB2 FGFR4 ligand binding and activation Signaling by EGFR Signaling by FGFR3 mutants Downstream signal transduction Signaling by activated point mutants of FGFR3 Fc epsilon receptor (FCERI) signaling Signaling by FGFR mutants Signaling by EGFR in Cancer PI3K/AKT Signaling in Cancer Adaptive Immune System IRS-mediated signalling PIP3 activates AKT signaling IGF1R signaling cascade IRS-related events triggered by IGF1R PI3K events in ERBB2 signaling Downstream signaling of activated FGFR FGFR3b ligand binding and activation FGFR3c ligand binding and activation FGFR1c ligand binding and activation FGFR2c ligand binding and activation FGFR ligand binding and activation Signaling by Insulin receptor Innate Immune System Signalling by NGF Insulin receptor signalling cascade IRS-related events Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane FGFR3 ligand binding and activation Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by FGFR FGFR2 ligand binding and activation FRS2-mediated cascade IRS-mediated signalling FGFR1 ligand binding and activation Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) PI3K Cascade
Drugs
Diseases
GWAS		Corneal structure ( 23291589)
Protein-protein Interactions		4 interactors: FGFR1 FGFR2 FGFR3 FGFR4
Entrez ID		2254
HPRD ID		02951
Ensembl ID		ENSG00000102678
Uniprot IDs		P31371
PDB IDs		1G82 1IHK
Enriched GO Terms of Interacting Partners?		Phosphatidylinositol-mediated Signaling Insulin Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Protein Autophosphorylation Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Lung Development Respiratory Tube Development Peptidyl-tyrosine Phosphorylation Fc Receptor Signaling Pathway Alveolar Secondary Septum Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Respiratory System Development Cell Fate Commitment Response To Insulin Cellular Response To Peptide Hormone Stimulus Lung Alveolus Development Cellular Response To Peptide Ventricular Zone Neuroblast Division Immune Response-regulating Cell Surface Receptor Signaling Pathway Orbitofrontal Cortex Development Positive Regulation Of Phospholipase Activity Positive Regulation Of MAPK Cascade Response To Peptide Hormone Immune Response-regulating Signaling Pathway Cellular Response To Organonitrogen Compound Midbrain Development Regulation Of Phospholipase Activity Response To Peptide Positive Regulation Of Lipase Activity Forebrain Ventricular Zone Progenitor Cell Division Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Cellular Response To Hormone Stimulus Response To Growth Factor Regulation Of MAPK Cascade Positive Regulation Of ERK1 And ERK2 Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Tube Development Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Lung Saccule Development Positive Regulation Of Cell Proliferation Response To Organonitrogen Compound
Tagcloud ?		activin conditional coordinate cues disrupt fate germ gonads impeded meiosis meiotic nodal p38 pgc pgcs primordial rescue severely sexual smad2 smad3 somatic sry suppressing testes triggers uncovered xy