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FGF5
Description
fibroblast growth factor 5
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Molecular Function
Fibroblast Growth Factor Receptor Binding
Growth Factor Activity
Biological Process
Signal Transduction
Cell-cell Signaling
Nervous System Development
Positive Regulation Of Cell Population Proliferation
Fibroblast Growth Factor Receptor Signaling Pathway
Glial Cell Differentiation
Neurogenesis
Signal Transduction Involved In Regulation Of Gene Expression
Regulation Of Cell Migration
Positive Regulation Of MAPK Cascade
Positive Regulation Of Cell Division
Pathways
Drugs
Diseases
GWAS
Apolipoprotein B levels (
32203549
)
Atrial fibrillation (
29892015
30061737
)
Blond vs. brown/black hair color (
30531825
)
Blood pressure (
21909110
24954895
)
Blood urea nitrogen levels (
29403010
31152163
)
Chronic kidney disease (
31152163
)
Coronary artery disease (
28714974
29212778
32469254
33020668
)
Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) (
28714975
)
Creatinine levels (
29403010
)
Diastolic blood pressure (
28871152
28135244
28739976
29403010
27841878
19430483
27736895
27618452
27618447
30487518
26390057
25249183
21909115
)
Diastolic blood pressure (cigarette smoking interaction) (
29455858
)
Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) (
29912962
)
Diastolic blood pressure x alcohol consumption interaction (2df test) (
29912962
)
Estimated glomerular filtration rate (
31152163
30604766
31015462
31451708
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
Glomerular filtration rate (
29403010
)
Gout (combined type) (
32238385
)
Hemoglobin levels (
32327693
)
Hypertension (
32709000
30487518
25249183
)
LDL cholesterol levels (
32203549
)
Male-pattern baldness (
28196072
27182965
29146897
)
Mean arterial pressure (
30487518
29403010
28871152
26390057
)
Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) (
29912962
)
Mean arterial pressure x alcohol consumption interaction (2df test) (
29912962
)
Medication use (agents acting on the renin-angiotensin system) (
31015401
)
Medication use (beta blocking agents) (
31015401
)
Medication use (calcium channel blockers) (
31015401
)
Medication use (diuretics) (
31015401
)
Medication use (HMG CoA reductase inhibitors) (
31015401
)
Monobrow (
27182965
)
Myocardial infarction (
33532862
)
Potassium levels (
29403010
)
PR interval (
32439900
)
Pulse pressure (
30487518
28739976
27841878
29403010
30578418
)
Pulse pressure x alcohol consumption interaction (2df test) (
29912962
)
Red blood cell count (
29403010
)
Refractive error (
32231278
)
Response to cognitive-behavioural therapy in major depressive disorder (
31123309
)
Serum uric acid levels (
30993211
29403010
)
Systolic blood pressure (
29403010
21909115
28871152
28135244
27841878
27736895
25249183
27618452
28739976
30487518
26390057
30578418
)
Systolic blood pressure (cigarette smoking interaction) (
29455858
)
Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) (
29912962
)
Systolic blood pressure x alcohol consumption interaction (2df test) (
29912962
)
Urate levels (
31578528
31985003
23263486
)
Interacting Genes
5 interacting genes:
FGFR1
FGFR2
FGFR3
FGFR4
PTX3
Entrez ID
2250
HPRD ID
01307
Ensembl ID
ENSG00000138675
Uniprot IDs
P12034
Q8NBG6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Fibroblast Growth Factor Receptor Activity
Fibroblast Growth Factor Binding
Positive Regulation Of Phospholipase Activity
Transmembrane Receptor Protein Tyrosine Kinase Activity
Positive Regulation Of Lipase Activity
Fibroblast Growth Factor Receptor Signaling Pathway
Protein Tyrosine Kinase Activity
Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development
Receptor Complex
Ventricular Zone Neuroblast Division
Orbitofrontal Cortex Development
Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Catalytic Activity
Forebrain Neuroblast Division
Forebrain Ventricular Zone Progenitor Cell Division
Biomineral Tissue Development
Lung-associated Mesenchyme Development
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of MAPK Cascade
Endochondral Bone Growth
Positive Regulation Of Hydrolase Activity
Protein Autophosphorylation
Protein Kinase Activity
Branching Involved In Salivary Gland Morphogenesis
Regulation Of Catalytic Activity
Heparin Binding
Kinase Activity
Bone Growth
Enzyme-linked Receptor Protein Signaling Pathway
Regulation Of MAPK Cascade
Positive Regulation Of ERK1 And ERK2 Cascade
Mesenchymal Cell Proliferation
Positive Regulation Of Mesenchymal Cell Proliferation
Positive Regulation Of Cardiac Muscle Cell Proliferation
Extracellular Region
Gland Morphogenesis
Cellular Response To Fibroblast Growth Factor Stimulus
Midbrain Development
Positive Regulation Of Cell Population Proliferation
Regulation Of Mesenchymal Cell Proliferation
Bone Morphogenesis
Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Heart Growth
Response To Fibroblast Growth Factor
Ureteric Bud Development
Regulation Of Cardiac Muscle Cell Proliferation
Regulation Of Developmental Growth
Mesonephric Tubule Development
Mesonephric Epithelium Development
Positive Regulation Of Organ Growth
Tagcloud
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