CCZ1B

Description		CCZ1B vacuolar protein trafficking and biogenesis associated
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Membrane Mon1-Ccz1 Complex Intracellular Membrane-bounded Organelle
	Molecular Function
	Biological Process	Vesicle-mediated Transport
Pathways		RAB GEFs exchange GTP for GDP on RABs RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 30820047) Body mass index ( 26426971) Bone mineral density (spine) ( 26911590) Mitochondrial heteroplasmy measurement ( 33731350) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		2 interacting genes: APP UBC
Entrez ID		221960
HPRD ID		12916
Ensembl ID		ENSG00000146574
Uniprot IDs		P86790 P86791
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Neuron Projection Maintenance RAGE Receptor Binding
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