PXDC1

Description		PX domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Phosphatidylinositol Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: RIPK1
Interacting Genes
Entrez ID		221749
HPRD ID		12854
Ensembl ID		ENSG00000168994
Uniprot IDs		Q5TGL8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Interleukin-6-mediated Signaling Pathway Ripoptosome Assembly Death Domain Binding Ripoptosome Assembly Involved In Necroptotic Process Ripoptosome Positive Regulation Of MiRNA Processing JUN Kinase Kinase Kinase Activity Necroptotic Signaling Pathway Death-inducing Signaling Complex Peptidyl-serine Autophosphorylation Positive Regulation Of Necroptotic Process Positive Regulation Of MiRNA-mediated Gene Silencing Positive Regulation Of Programmed Necrotic Cell Death Positive Regulation Of Macrophage Differentiation Regulation Of MiRNA Processing Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Necroptotic Process Regulation Of Regulatory NcRNA Processing Death Receptor Binding Positive Regulation Of Execution Phase Of Apoptosis Programmed Necrotic Cell Death Negative Regulation Of Necroptotic Process Negative Regulation Of Programmed Necrotic Cell Death Amyloid Fibril Formation Regulation Of Macrophage Differentiation T Cell Apoptotic Process Regulation Of Post-transcriptional Gene Silencing Regulation Of MiRNA-mediated Gene Silencing Regulation Of Necroptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Lymphocyte Apoptotic Process Regulation Of Programmed Necrotic Cell Death Peptidyl-serine Phosphorylation Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Leukocyte Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Interleukin-8 Production Cellular Response To Hydrogen Peroxide Canonical NF-kappaB Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Signaling Adaptor Activity Regulation Of Interleukin-8 Production
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