KDM1B

Description		lysine demethylase 1B
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GO Annotations	Cellular Component	Chromatin Nucleosome Nucleus Nucleoplasm Chromosome
	Molecular Function	Protein Binding Zinc Ion Binding Oxidoreductase Activity Histone Demethylase Activity Histone H3K4 Demethylase Activity Histone Binding Metal Ion Binding Flavin Adenine Dinucleotide Binding FAD Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity
	Biological Process	Chromatin Organization Epigenetic Regulation Of Gene Expression Epigenetic Programing Of Female Pronucleus Transcription Initiation-coupled Chromatin Remodeling Genomic Imprinting
Pathways		HDMs demethylate histones UCH proteinases NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015 30061737)
Interacting Genes		2 interacting genes: H3-4 UBE2D3
Entrez ID		221656
HPRD ID		18524
Ensembl ID		ENSG00000165097
Uniprot IDs		H0Y6H0 Q8NB78
PDB IDs		4FWE 4FWF 4FWJ 4GU0 4GU1 4GUR 4GUS 4GUT 4GUU 4HSU 6R1U 6R25 7XE1 7XE2 7XE3
Enriched GO Terms of Interacting Partners?
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