SPATA13

Description		spermatogenesis associated 13
Image		No pdb structure
GO Annotations	Cellular Component	Podosome Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Lamellipodium Filopodium Ruffle Membrane Cell Projection Anchoring Junction
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Cell Migration Lamellipodium Assembly Regulation Of Cell Migration Filopodium Assembly Regulation Of Small GTPase Mediated Signal Transduction
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Autoimmune thyroid disease ( 32581359) Cerebral cortical growth ( 29682794) Depression and alcohol dependence ( 22064162) Heel bone mineral density ( 30598549) Hypothyroidism ( 27182965) Mean spheric corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Orofacial clefts ( 22419666) Plateletcrit ( 32888494) Thyroid stimulating hormone levels ( 30367059 32769997) Tumor necrosis factor receptor II (red blood cell fatty acid level interaction) ( 28820441)
Interacting Genes		3 interacting genes: CDC42 GALK1 KHDRBS1
Entrez ID		221178
HPRD ID		15427
Ensembl ID		ENSG00000182957
Uniprot IDs		A0A024RDM6 B4DMC2 E9PFR9 Q96N96
PDB IDs
Enriched GO Terms of Interacting Partners?		GBD Domain Binding Storage Vacuole Glycolytic Process From Galactose Galactokinase Activity Galactitol Metabolic Process Grb2-Sos Complex Apolipoprotein A-I Receptor Binding Endothelin Receptor Signaling Pathway Involved In Heart Process Neuropilin Signaling Pathway Galactose Binding Galactose Catabolic Process Via UDP-galactose, Leloir Pathway Positive Regulation Of Pinocytosis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Galactose Catabolic Process Positive Regulation Of RNA Export From Nucleus Leading Edge Membrane Thioesterase Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Neuron Fate Determination Establishment Of Golgi Localization Golgi Transport Complex Galactose Metabolic Process Endothelin Receptor Signaling Pathway Phosphotransferase Activity, Alcohol Group As Acceptor Positive Regulation Of Pseudopodium Assembly Golgi Localization Regulation Of Attachment Of Spindle Microtubules To Kinetochore Establishment Of Apical/basal Cell Polarity Dendritic Cell Migration Establishment Of Monopolar Cell Polarity GTP-dependent Protein Binding Heart Contraction Cardiac Conduction System Development Embryonic Heart Tube Development Dendritic Spine Morphogenesis Establishment Of Epithelial Cell Apical/basal Polarity Filopodium Assembly Establishment Or Maintenance Of Monopolar Cell Polarity Cell Migration Involved In Heart Development Polarized Epithelial Cell Differentiation Glycolytic Process Through Glucose-6-phosphate Carbohydrate Phosphorylation Glycolytic Process Through Fructose-6-phosphate Poly(U) RNA Binding Regulation Of RNA Export From Nucleus Poly(A) Binding Spindle Midzone Positive Regulation Of Lamellipodium Assembly
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