MICU2

Description		mitochondrial calcium uptake 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane Calcium Channel Complex Uniplex Complex
	Molecular Function	Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Protein Heterodimerization Activity Calcium Ion Sensor Activity
	Biological Process	Mitochondrial Calcium Ion Transmembrane Transport Calcium Import Into The Mitochondrion Mitochondrial Calcium Ion Homeostasis Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Mitochondrial Calcium Ion Concentration Cellular Response To Calcium Ion
Pathways		Mitochondrial calcium ion transport Processing of SMDT1 Mitochondrial protein degradation
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732)
Interacting Genes		3 interacting genes: GPRASP2 MBP UBC
Entrez ID		221154
HPRD ID		16852
Ensembl ID		ENSG00000165487
Uniprot IDs		A0A0S2Z6V5 Q8IYU8
PDB IDs		6AGH 6IIH 6K7Y 6LB7 6LB8 6LE5 6WDN 6WDO 6XJV 6XJX 6XQN 6XQO
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metalloendopeptidase Activity Regulation Of Metallopeptidase Activity Internode Region Of Axon Compact Myelin Negative Regulation Of Heterotypic Cell-cell Adhesion Structural Constituent Of Myelin Sheath Positive Regulation Of Peptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Multicellular Organismal-level Homeostasis Protein Tag Activity Regulation Of Endopeptidase Activity Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Hematopoietic Stem Cell Homeostasis Myelin Sheath Maintenance Of Blood-brain Barrier
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