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RASGEF1A
Gene Name
RasGEF domain family, member 1A
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Molecular Function
Ras Guanyl-nucleotide Exchange Factor Activity
Biological Process
Small GTPase Mediated Signal Transduction
Cell Migration
Positive Regulation Of Ras GTPase Activity
Positive Regulation Of Ras Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS
Hirschsprung's disease (
19196962
)
Obesity-related traits (
23251661
)
Protein-protein Interactions
1 interactors:
NEDD4
Entrez ID
221002
HPRD ID
15211
Ensembl ID
ENSG00000198915
Uniprot IDs
Q8N9B8
PDB IDs
Enriched GO Terms of Interacting Partners
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Transmission Of Virus
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Development Involved In Symbiotic Interaction
Progesterone Receptor Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Glucocorticoid Receptor Signaling Pathway
Protein Targeting To Lysosome
Negative Regulation Of Sodium Ion Transport
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Protein Localization To Lysosome
Receptor Catabolic Process
Protein Targeting To Vacuole
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Establishment Of Protein Localization To Vacuole
Regulation Of Potassium Ion Transmembrane Transporter Activity
Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Protein K63-linked Ubiquitination
Endocardial Cushion Development
Regulation Of Potassium Ion Transmembrane Transport
Protein Monoubiquitination
Receptor Internalization
Lysosomal Transport
Neuromuscular Junction Development
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cellular Response To UV
Regulation Of Potassium Ion Transport
Outflow Tract Morphogenesis
Regulation Of Sodium Ion Transport
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Dendrite Morphogenesis
Intracellular Steroid Hormone Receptor Signaling Pathway
Vacuolar Transport
Receptor Metabolic Process
Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Synapse Organization
Regulation Of Synapse Structure Or Activity
Cellular Response To Light Stimulus
Negative Regulation Of Ion Transport
Interaction With Host
Regulation Of Dendrite Development
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Positive Regulation Of Nucleocytoplasmic Transport
Response To Calcium Ion
Response To UV
Cellular Response To Radiation
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Transmembrane Transporter Activity
Protein Polyubiquitination
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