MS4A2

Gene Name		membrane-spanning 4-domains, subfamily A, member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Fc-epsilon Receptor I Complex Membrane Raft
	Molecular Function	IgE Receptor Activity IgE Binding Protein Kinase Binding SH2 Domain Binding Phosphoprotein Binding
	Biological Process	Inflammatory Response Immune Response Activation Of Phospholipase C Activity Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Mast Cell Degranulation Innate Immune Response Cytokine Secretion Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Pathways		FCERI mediated NF-kB activation Fc epsilon receptor (FCERI) signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization Role of LAT2/NTAL/LAB on calcium mobilization Innate Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: AKT1 APP FCER1A GRB2 HSP90AA1 LYN PRKCD PTPN11 PTPN6 SYK
Entrez ID		2206
HPRD ID		00915
Ensembl ID
Uniprot IDs		Q01362
PDB IDs
Enriched GO Terms of Interacting Partners?		Immune Response-regulating Cell Surface Receptor Signaling Pathway Innate Immune Response Immune Response-regulating Signaling Pathway Fc Receptor Signaling Pathway Platelet Activation Immune Response Defense Response Blood Coagulation Hemostasis Regulation Of Cell Activation Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Body Fluid Levels Positive Regulation Of Cell Activation Wound Healing Regulation Of MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Wounding Regulation Of Cell-cell Adhesion Regulation Of Protein Kinase Activity Regulation Of Cellular Amino Acid Metabolic Process Immune System Process Regulation Of Immune System Process Regulation Of Phosphorylation Regulation Of Kinase Activity T Cell Costimulation Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Phosphorus Metabolic Process Fc-epsilon Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Cell-cell Adhesion Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of MAP Kinase Activity Regulation Of T Cell Activation Regulation Of Protein Phosphorylation Regulation Of Cell Adhesion Positive Regulation Of Immune Response Regulation Of Cell Adhesion Mediated By Integrin Cell Activation Cell Surface Receptor Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Cell Adhesion Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Regulation Of Lymphocyte Activation
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