FAU

Description		FAU ubiquitin like and ribosomal protein S30 fusion
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GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Ribosome Small Ribosomal Subunit Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Ribonucleoprotein Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Protein Tag Activity Ubiquitin Protein Ligase Binding
	Biological Process	Ribosomal Small Subunit Assembly Cytoplasmic Translation Innate Immune Response In Mucosa Translation Protein Ubiquitination Antibacterial Humoral Response Modification-dependent Protein Catabolic Process Defense Response To Gram-positive Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency SARS-CoV-1 modulates host translation machinery SARS-CoV-2 modulates host translation machinery Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: COPS6 IL7R TAF7 USP16
Entrez ID		2197
HPRD ID		00002
Ensembl ID		ENSG00000149806
Uniprot IDs		P62861
PDB IDs		2L7R 4UG0 4V6X 5A2Q 5AJ0 5FLX 5OA3 5T2C 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6Y0G 6Y2L 6Y57 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZUO 6ZV6 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I 7QP6 7QP7 7R4X 7TQL 7WTS 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0 7XNX 7XNY 8BS3 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IFD 8IFE 8JDJ 8JDK 8JDL 8JDM 8K2C 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPK 8PPL 8QOI 8T4S 8UKB 8XP2 8XP3 8XSX 8XSY 8XSZ 8XXL 8XXM 8XXN 8Y0W 8Y0X 8YOO 8YOP 8ZDB 9BKD 9BLN 9C3H 9G8M 9G8O
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MHC Class I Biosynthetic Process Protein Modification By Small Protein Removal Positive Regulation Of Ribosome Biogenesis Negative Regulation Of T Cell Mediated Cytotoxicity Nucleoplasm Interleukin-7-mediated Signaling Pathway Positive Regulation Of T Cell Differentiation In Thymus Interleukin-7 Receptor Activity TFIIH-class Transcription Factor Complex Binding Regulation Of MHC Class I Biosynthetic Process Spermine Transport P-TEFb Complex Binding Histone H3K27me3 Reader Activity Negative Regulation Of MHC Class II Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of Ribosome Biogenesis Positive Regulation Of Translational Elongation Monoubiquitinated Protein Deubiquitination Regulation Of Translational Elongation Mitotic Nuclear Division Histone H2A Deubiquitinase Activity Protein Deneddylation Metal-dependent Deubiquitinase Activity Nuclear Vitamin D Receptor Binding
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