ACSL1

Gene Name		acyl-CoA synthetase long-chain family member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Long-chain Fatty Acid-CoA Ligase Activity ATP Binding
	Biological Process	Long-chain Fatty Acid Metabolic Process Response To Nutrient Lipid Biosynthetic Process Response To Organic Cyclic Compound Triglyceride Biosynthetic Process Adiponectin-activated Signaling Pathway Unsaturated Fatty Acid Metabolic Process Response To Oleic Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Alpha-linolenic Acid Metabolic Process Xenobiotic Catabolic Process Response To Drug Linoleic Acid Metabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Long-chain Fatty Acid Import Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways		PPARA activates gene expression Fatty Acyl-CoA Biosynthesis Fatty acid, triacylglycerol, and ketone body metabolism alpha-linolenic acid (ALA) metabolism Metabolism of lipids and lipoproteins alpha-linolenic (omega3) and linoleic (omega6) acid metabolism Linoleic acid (LA) metabolism Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Triglyceride Biosynthesis Synthesis of very long-chain fatty acyl-CoAs
Drugs		Adenosine monophosphate Adenosine triphosphate
Diseases
GWAS
Protein-protein Interactions		1 interactors: NR3C2
Entrez ID		2180
HPRD ID		01068
Ensembl ID		ENSG00000151726
Uniprot IDs		B7Z452 E7EPM6 P33121
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Sodium Ion Homeostasis Sodium Ion Homeostasis Excretion
Tagcloud ?		2a adenovirus atf6 atgl augmented cardiomyocyte channeling chop create creation droplets eif2a esterified explored fatty grp78 incubated inefficient lipid lipids nefa neutral oleate palmitate ppargamma protects storage stored upregulation