FAAH

Description		fatty acid amide hydrolase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Cytoskeleton Endomembrane System Membrane Organelle Membrane Presynapse Postsynapse Glutamatergic Synapse
	Molecular Function	Amidase Activity Protein Binding Phospholipid Binding Lipid Binding Hydrolase Activity Hydrolase Activity, Acting On Ester Bonds Fatty Acid Amide Hydrolase Activity Identical Protein Binding Monoacylglycerol Lipase Activity
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Catabolic Process Lipid Catabolic Process Arachidonate Metabolic Process Positive Regulation Of Vasoconstriction Monoacylglycerol Catabolic Process Regulation Of Trans-synaptic Signaling By Endocannabinoid, Modulating Synaptic Transmission
Pathways		Arachidonate metabolism
Drugs		Thiopental Methoxy arachidonyl fluorophosphonate 1-Dodecanol 4-(quinolin-3-ylmethyl)piperidine-1-carboxylic acid 4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzyl)piperidine-1-carboxylic acid Fostamatinib Medical Cannabis Nabiximols
Diseases
GWAS		Body mass index ( 26426971) Lipid or lipoprotein levels ( 23696881) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 33031748)
Novel Interacting Genes		1 novel interacting genes: SLC2A1
Interacting Genes		1 interacting genes: NOTCH2NLA
Entrez ID		2166
HPRD ID		04244
Ensembl ID		ENSG00000117480
Uniprot IDs		O00519
PDB IDs
Enriched GO Terms of Interacting Partners?		Cerebral Cortex Development Fucose Transmembrane Transporter Activity Glucose Transporter Complex Fucose Transmembrane Transport Response To Thyroglobulin Triiodothyronine D-glucose Import Across Plasma Membrane Long-chain Fatty Acid Import Across Plasma Membrane Dehydroascorbic Acid Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity L-ascorbic Acid Metabolic Process Dehydroascorbic Acid Transport Female Pronucleus Long-chain Fatty Acid Import Into Cell Lipid Import Into Cell Female Germ Cell Nucleus Long-chain Fatty Acid Transmembrane Transporter Activity Cellular Hyperosmotic Response D-glucose Import Xenobiotic Transmembrane Transporter Activity Notch Binding Hyperosmotic Response D-glucose Transmembrane Transport Hexose Transmembrane Transport Cellular Response To Glucose Starvation Cellular Response To Osmotic Stress Carbohydrate Transport Vitamin Transport Xenobiotic Transport Photoreceptor Cell Maintenance Carbohydrate Transmembrane Transport Long-chain Fatty Acid Transport Intercalated Disc Positive Regulation Of Notch Signaling Pathway Cortical Actin Cytoskeleton Photoreceptor Inner Segment Response To Osmotic Stress Cellular Response To Mechanical Stimulus Caveola Transport Across Blood-brain Barrier Female Pregnancy Fatty Acid Transport Regulation Of Notch Signaling Pathway Kinase Binding Melanosome Sarcolemma Notch Signaling Pathway Blood Microparticle Organic Acid Transmembrane Transport Carboxylic Acid Transmembrane Transport Monocarboxylic Acid Transport
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