EYA1

Gene Name		EYA transcriptional coactivator and phosphatase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	RNA Binding Protein Tyrosine Phosphatase Activity Protein Binding Metal Ion Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Metanephros Development Branching Involved In Ureteric Bud Morphogenesis Outflow Tract Morphogenesis Double-strand Break Repair Transcription, DNA-templated Pattern Specification Process Sensory Perception Of Sound Anatomical Structure Morphogenesis Response To Ionizing Radiation Striated Muscle Tissue Development Histone Dephosphorylation Protein Sumoylation Cellular Protein Localization Establishment Or Maintenance Of Apical/basal Cell Polarity Peptidyl-tyrosine Dephosphorylation Aorta Morphogenesis Outer Ear Morphogenesis Middle Ear Morphogenesis Regulation Of Neuron Differentiation Positive Regulation Of DNA Repair Positive Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Neuron Fate Specification Embryonic Skeletal System Morphogenesis Semicircular Canal Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Pharyngeal System Development Lung Epithelial Cell Differentiation Otic Vesicle Morphogenesis Positive Regulation Of Secondary Heart Field Cardioblast Proliferation Cochlea Morphogenesis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Sleepiness ( 17903308)
Protein-protein Interactions		7 interactors: DACH1 GNAI2 GNAZ GSK3B SIX1 SIX2 SIX3
Entrez ID		2138
HPRD ID		03388
Ensembl ID		ENSG00000104313
Uniprot IDs		A6NCB9 Q99502
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Localization To Organelle Negative Regulation Of Biosynthetic Process Protein Localization To Nucleus Regulation Of Branching Involved In Ureteric Bud Morphogenesis Regulation Of Cell Proliferation Mesenchyme Development Middle Ear Morphogenesis Cell Proliferation Nucleocytoplasmic Transport Nuclear Transport Cell Migration Regulation Of Transcription From RNA Polymerase II Promoter Cell Fate Commitment Cell Motility Stem Cell Differentiation Embryonic Organ Morphogenesis Developmental Induction Negative Regulation Of Cellular Metabolic Process Organ Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Embryonic Cranial Skeleton Morphogenesis Regulation Of Morphogenesis Of A Branching Structure Locomotion Nephron Morphogenesis Positive Regulation Of Cellular Metabolic Process Pattern Specification Process Embryonic Organ Development Positive Regulation Of Transcription, DNA-templated Neuroblast Migration Mesenchymal Stem Cell Proliferation Cellular Protein Localization Cell Fate Specification Epithelial Cell Differentiation Kidney Morphogenesis Regulation Of Neuron Differentiation Metanephros Development Movement Of Cell Or Subcellular Component Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Stem Cell Proliferation Axis Specification Sensory Organ Development Positive Regulation Of Gene Expression Protein Import Into Nucleus Nuclear Import Ear Morphogenesis Regulation Of Cell Differentiation Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Type B Pancreatic Cell Development
Tagcloud ?		amphiphysin bmp7 bred cited1 e13 e15 endowment ensures gammah2ax hypo lhx1 mdm mesenchyme metanephroi nephrogenic nephron npc organogenesis patchy pax2 pax8 pockets renewing sall1 six2 superficially susceptibile thinning wnt4