EXTL3

Name	exostosin like glycosyltransferase 3
Structure
Interactors	4 interactors: ATXN1 DSCR9 LCOR PLEKHA5
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Magnesium Ion Binding Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase Activity Protein Binding Acetylglucosaminyltransferase Activity Protein-hormone Receptor Activity Transferase Activity Glycosyltransferase Activity Metal Ion Binding
	Biological Process	Protein Glycosylation Positive Regulation Of Keratinocyte Proliferation Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Cell Growth Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Keratinocyte Differentiation Negative Regulation Of Inflammatory Response Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Inflammatory Response To Wounding Negative Regulation Of Inflammatory Response To Wounding Negative Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Detection Of Glucose
Pathways	HS-GAG biosynthesis XBP1(S) activates chaperone genes
GWAS	Height ( 25429064 ) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355 ) Moderate-to-late spontaneous preterm birth ( 31194736 )
Entrez ID	2137
HPRD ID	09306
Ensembl ID	ENSG00000012232
Uniprot IDs	A0A384NPY9 O43909
PDB IDs	7AU2 7AUA 8OG1 8OG4