EXTL2

Description		exostosin like glycosyltransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane
	Molecular Function	Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase Activity Protein Binding Glycosaminoglycan Binding Acetylglucosaminyltransferase Activity Transferase Activity Glycosyltransferase Activity Manganese Ion Binding Alpha-1,4-N-acetylgalactosaminyltransferase Activity Metal Ion Binding Glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity
	Biological Process	N-acetylglucosamine Metabolic Process Heparan Sulfate Proteoglycan Biosynthetic Process UDP-N-acetylgalactosamine Metabolic Process
Pathways		HS-GAG biosynthesis XBP1(S) activates chaperone genes
Drugs		Uridine-Diphosphate-N-Acetylgalactosamine Uridine-Diphosphate-N-Acetylglucosamine Uridine-5'-Diphosphate
Diseases
GWAS		Multiple sclerosis ( 21833088)
Interacting Genes		1 interacting genes: TRIM54
Entrez ID		2135
HPRD ID		03876
Ensembl ID		ENSG00000162694
Uniprot IDs		F5GZK1 Q8N8F1 Q9UBQ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Microtubule Depolymerization Negative Regulation Of Microtubule Depolymerization Microtubule Associated Complex Negative Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Supramolecular Fiber Organization Regulation Of Protein Depolymerization Z Disc Negative Regulation Of Cytoskeleton Organization Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Protein-containing Complex Disassembly Regulation Of Protein-containing Complex Disassembly
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