EPHB4

Gene Name		EPH receptor B4
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Gene Ontology Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity Protein Binding ATP Binding
	Biological Process	Angiogenesis Cell Migration Involved In Sprouting Angiogenesis Heart Morphogenesis Cell Adhesion Axon Guidance Peptidyl-tyrosine Phosphorylation Protein Autophosphorylation Ephrin Receptor Signaling Pathway
Pathways		EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
Protein-protein Interactions		4 interactors: APP EFNB2 GRIN1 SDC3
Entrez ID		2050
HPRD ID		02481
Ensembl ID		ENSG00000196411
Uniprot IDs		P54760 Q541P7 Q7Z635 Q96L35
PDB IDs		2BBA 2E7H 2HLE 2QKQ 2VWU 2VWV 2VWW 2VWX 2VWY 2VWZ 2VX0 2VX1 2X9F 2XVD 4AW5 4BB4
Enriched GO Terms of Interacting Partners?		Suckling Behavior Response To Light Stimulus Mating Behavior Axon Guidance Ionotropic Glutamate Receptor Signaling Pathway Response To Radiation Mating Response To External Stimulus Glutamate Receptor Signaling Pathway Visual Learning Axonogenesis Visual Behavior Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Associative Learning Neuron Projection Morphogenesis Regulation Of Synapse Structure Or Activity Ephrin Receptor Signaling Pathway Feeding Behavior Cell Morphogenesis Involved In Differentiation Adult Locomotory Behavior Neuron Projection Development Propylene Metabolic Process Cell Projection Morphogenesis Neuromuscular Process Cell Part Morphogenesis Learning Neuron Development Adult Behavior Synaptic Growth At Neuromuscular Junction Olfactory Learning Cell Morphogenesis Response To Abiotic Stimulus Neuron Differentiation Cell Projection Organization Collateral Sprouting In Absence Of Injury Pons Maturation Locomotory Behavior Locomotion Learning Or Memory Collateral Sprouting Axon Midline Choice Point Recognition Cellular Response To Manganese Ion Cognition Cellular Calcium Ion Homeostasis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Movement Of Cell Or Subcellular Component Calcium Ion Homeostasis Axon Choice Point Recognition
Tagcloud ?		advantages autophosphorylation barely bhg712 explained fibroblasts fibrosarcoma heterogeneous intraperitoneal liposarcoma malignancies malignancy mesenchymal metastases mfh nvp residual sarcoma sarcomas soft spots sts summary synovial transmigration tumorigenesis vimentin vitality xenograft