NLRP11

Description		NLR family pyrin domain containing 11
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding ATP Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Ascorbate As One Donor, And Incorporation Of One Atom Of Oxygen
	Biological Process	Regulation Of Inflammatory Response
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 23377640) Menopause (age at onset) ( 22267201 26414677) Multiple sclerosis (severity) ( 19010793) Offspring birth weight ( 31043758)
Interacting Genes		2 interacting genes: RNF10 USP7
Entrez ID		204801
HPRD ID		10110
Ensembl ID		ENSG00000179873
Uniprot IDs		P59045
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Establishment Of Protein Localization To Chromosome Monoubiquitinated Protein Deubiquitination Regulation Of Establishment Of Protein Localization To Telomere DNA Alkylation Repair Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Retrograde Transport, Endosome To Golgi Protein Ubiquitination Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Postsynapse To Nucleus Signaling Pathway Negative Regulation Of Schwann Cell Proliferation Extrinsic Component Of Postsynaptic Density Membrane Transcription-coupled Nucleotide-excision Repair Protein Modification By Small Protein Conjugation Regulation Of Telomere Capping Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Negative Regulation Of Gluconeogenesis K48-linked Deubiquitinase Activity Positive Regulation Of Myelination Negative Regulation Of Glial Cell Proliferation Post-translational Protein Modification Deubiquitinase Activity Proteolysis Regulation Of Glial Cell Proliferation Negative Regulation Of Gliogenesis Regulation Of Myelination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Postsynaptic Signal Transduction Nucleotide-excision Repair Regulation Of Gluconeogenesis Protein Monoubiquitination Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process TORC1 Signaling Cysteine-type Endopeptidase Activity Negative Regulation Of TORC1 Signaling P53 Binding Protein Autoubiquitination Protein Modification Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Cysteine-type Deubiquitinase Activity Protein Deubiquitination Autophagosome Assembly Regulation Of TORC1 Signaling Negative Regulation Of TOR Signaling TOR Signaling Regulation Of Glucose Metabolic Process Cytosolic Ribosome Regulation Of Gliogenesis Autophagosome Organization Negative Regulation Of Autophagy
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