CCDC107

Description		coiled-coil domain containing 107
Image		No pdb structure
GO Annotations	Cellular Component	Membrane
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Severe insulin-deficient type 2 diabetes ( 34737425)
Interacting Genes		9 interacting genes: ADGRE2 ADIPOQ APP GRM2 KPNA2 SLC35B1 TNF UBQLN4 UNC93B1
Entrez ID		203260
HPRD ID		14545
Ensembl ID		ENSG00000159884
Uniprot IDs		Q8WV48
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cytokine Production Positive Regulation Of Chemokine Production Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Astrocyte Projection Regulation Of Cytokine Production Positive Regulation Of Membrane Protein Ectodomain Proteolysis Endoplasmic Reticulum Positive Regulation Of CAMP/PKA Signal Transduction Toll-like Receptor 3 Signaling Pathway Astrocyte Activation Negative Regulation Of Blood Circulation Modulation Of Chemical Synaptic Transmission Regulation Of Interleukin-6 Production Regulation Of Amyloid-beta Clearance Positive Regulation Of Small Molecule Metabolic Process Positive Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Membrane Protein Ectodomain Proteolysis Regulation Of DNA Metabolic Process Endolysosomal Toll-like Receptor Signaling Pathway Negative Regulation Of MiRNA Transcription Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Regulation Of Secretion By Cell Non-canonical NF-kappaB Signal Transduction Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Gene Expression Response To Stress Negative Regulation Of Synaptic Transmission Regulation Of Secretion Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of CAMP/PKA Signal Transduction Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Glutamate Receptor Signaling Pathway Positive Regulation Of Phosphate Metabolic Process Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Macrophage Activation Regulation Of ERK1 And ERK2 Cascade Amylin Binding Response To Amyloid-beta Positive Regulation Of Toll Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Localization
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