FBXO15

Description		F-box protein 15
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Binding
	Biological Process
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Cervical cancer ( 28806749) Coronary artery calcification ( 23870195) Diastolic blood pressure (alcohol consumption interaction) ( 24376456) Longevity (100 years and older) ( 33948810) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Metabolite levels ( 23823483) Sleep (1/2-day periodicity) ( 33075057) Sleep duration ( 23728906) Smooth-surface caries ( 24556642) Thyroid hormone levels ( 23408906)
Interacting Genes		2 interacting genes: CRLS1 SKP1
Entrez ID		201456
HPRD ID		16435
Ensembl ID		ENSG00000141665
Uniprot IDs		Q8NCQ5
PDB IDs
Enriched GO Terms of Interacting Partners?		F-box Domain Binding Cul7-RING Ubiquitin Ligase Complex Ubiquitin Ligase Complex Scaffold Activity 2-acylglycerol-3-phosphate O-acyltransferase Activity Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylglycerol Biosynthetic Process Cardiolipin Biosynthetic Process Cardiolipin Synthase (CMP-forming) Ubiquitin Ligase Activator Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Cardiolipin Metabolic Process 1-acylglycerol-3-phosphate O-acyltransferase Activity Maintenance Of Protein Location In Nucleus PcG Protein Complex Cullin Family Protein Binding Molecular Function Activator Activity Positive Regulation Of Epithelial Cell Apoptotic Process Phosphatidylglycerol Metabolic Process Maintenance Of Protein Localization In Organelle Maintenance Of Protein Location Regulation Of Epithelial Cell Apoptotic Process Maintenance Of Protein Location In Cell Protein Monoubiquitination SCF Ubiquitin Ligase Complex SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Axon Development Maintenance Of Location In Cell Maintenance Of Location Ubiquitin-like Ligase-substrate Adaptor Activity Beta-catenin Binding Protein K48-linked Ubiquitination
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