CEP112

Description		centrosomal protein 112
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Plasma Membrane Inhibitory Synapse
	Molecular Function	Protein Binding
	Biological Process	Receptor Localization To Synapse
Pathways
Drugs
Diseases
GWAS		β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Blood protein levels ( 23696881) Brain morphology (MOSTest) ( 32665545) Central corneal thickness ( 32528159) Chin dimples ( 27182965) Iris color (b* coordinate) ( 30895295) Plateletcrit ( 32888494) Post bronchodilator FEV1 ( 26634245) Total body bone mineral density ( 29304378) Youthful appearance (self-reported) ( 32339537)
Novel Interacting Genes		1 novel interacting genes: ERN1
Interacting Genes		1 interacting genes: FBXO7
Entrez ID		201134
HPRD ID		11336
Ensembl ID		ENSG00000154240
Uniprot IDs		F5GYE8 Q8N8E3
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Endonucleolytic Cleavage And Ligation Ire1 Complex Regulation Of Macroautophagy Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite AIP1-IRE1 Complex IRE1-RACK1-PP2A Complex Lewy Body Core IRE1-TRAF2-ASK1 Complex Regulation Of Autophagy IRE1-mediated Unfolded Protein Response Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Platelet-derived Growth Factor Receptor Binding Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Unfolded Protein Insulin Metabolic Process Protein-containing Complex Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Vascular Endothelial Growth Factor Stimulus Cellular Response To Topologically Incorrect Protein RNA Nuclease Activity Positive Regulation Of Mitophagy Positive Regulation Of Autophagy Of Mitochondrion Protein Targeting To Mitochondrion Macromolecule Catabolic Process ADP Binding Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Regulation Of Endoplasmic Reticulum Unfolded Protein Response RNA Endonuclease Activity Endothelial Cell Proliferation Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of RNA Splicing Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Hsp90 Protein Binding Hsp70 Protein Binding Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitophagy Nuclear Inner Membrane Regulation Of Autophagy Of Mitochondrion Protein Modification Process Cellular Response To Glucose Stimulus Endonuclease Activity Mitochondrion Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Carbohydrate Stimulus Cellular Response To Hydrogen Peroxide Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
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