ELK4

Description		ETS transcription factor ELK4
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Prostate cancer
GWAS
Novel Interacting Genes		1 novel interacting genes: FGFR2
Interacting Genes		11 interacting genes: BRCA1 FOS ID1 ID2 ID3 MAPK1 MAPK11 MAPK3 MAPK7 MAPK8 SRF
Entrez ID		2005
HPRD ID		02592
Ensembl ID		ENSG00000158711
Uniprot IDs		P28324 Q8IXL1
PDB IDs		1BC7 1BC8 1HBX 1K6O
Enriched GO Terms of Interacting Partners?		MAP Kinase Activity Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Lung Morphogenesis Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Animal Organ Morphogenesis Cellular Senescence Cell Differentiation Regulation Of Developmental Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process MAPK Cascade Face Development Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Tumor Necrosis Factor Protein Kinase Activity Hematopoietic Or Lymphoid Organ Development Cellular Response To Oxygen-containing Compound Cellular Response To Nutrient Levels Positive Regulation Of Nucleobase-containing Compound Metabolic Process Heart Development Animal Organ Development Regulation Of Multicellular Organismal Development Response To Cytokine Cellular Developmental Process Nucleoplasm Response To Peptide Regulation Of Multicellular Organismal Process Regulation Of Macromolecule Metabolic Process Thyroid Gland Development Response To Tumor Necrosis Factor Response To Lipopolysaccharide Astrocyte Differentiation Interleukin-34-mediated Signaling Pathway Response To Growth Factor Regulation Of Cell Differentiation Kinase Activity Cellular Response To Stress Regulation Of DNA-templated Transcription Response To Molecule Of Bacterial Origin Regulation Of RNA Biosynthetic Process Protein Serine Kinase Activity Regulation Of Osteoblast Differentiation Regulation Of Golgi Inheritance Transcription Regulator Inhibitor Activity
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