ELK3

Name	ETS transcription factor ELK3
Structure	No pdb structure
Novel Interactors	1 novel interactors: APAF1
Interactors	16 interactors: APP BPIFA1 CRK CTBP1 ID2 MAPK14 MAPK8 MAPK9 NFIA NFIB NFIC PFDN5 PIAS1 SP4 TCF3 TOP1
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Mitochondrion
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Purine-rich Negative Regulatory Element Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Signal Transduction Cell Differentiation Wound Healing Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
GWAS	Acute lymphoblastic leukemia in childhood (B cell precursor) ( 27694927 29632299 ) B-cell acute lymphoblastic leukaemia ( 31767839 ) Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382 ) Small intestine neuroendocrine tumor ( 27492634 ) Thyroid stimulating hormone levels ( 32769997 ) Vaginal microbiome composition (community state type) ( 32723796 )
Entrez ID	2004
HPRD ID	02593
Ensembl ID	ENSG00000111145
Uniprot IDs	P41970
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Nucleobase-containing Compound Metabolic Process MAP Kinase Activity Cellular Senescence Nucleus Negative Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Response To Radiation JUN Kinase Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of Metabolic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Macromolecule Biosynthetic Process Response To Light Stimulus DNA Replication Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Glial Cell Fate Specification Negative Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Binding Positive Regulation Of Macromolecule Metabolic Process Enzyme Binding Nucleoplasm Transcription Corepressor Activity Protein-containing Complex Protein Domain Specific Binding Retina Development In Camera-type Eye Positive Regulation Of Metabolic Process Developmental Process Response To Yeast Exit From Mitosis Rhythmic Process Cellular Developmental Process White Fat Cell Differentiation Cellular Response To Oxygen-containing Compound