ELF1

Gene Name		E74-like factor 1 (ets domain transcription factor)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Regulation Of Cytokine Production Transcription From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of T Cell Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 23266558) Systemic lupus erythematosus ( 23273568 21044949)
Protein-protein Interactions		8 interactors: HMGA1 HOXC13 NFKB1 NFYA NFYB RB1 REL SP1
Entrez ID		1997
HPRD ID		01808
Ensembl ID		ENSG00000120690
Uniprot IDs		P32519 Q6MZZ4
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Enucleate Erythrocyte Differentiation Nitrogen Compound Metabolic Process Regulation Of Interleukin-12 Biosynthetic Process NIK/NF-kappaB Signaling Regulation Of Metabolic Process I-kappaB Kinase/NF-kappaB Signaling Regulation Of Interleukin-12 Production Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Sequestering Of Nodal From Receptor Via Nodal Binding Negative Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Gene Expression Erythrocyte Differentiation Regulation Of Cytokine Biosynthetic Process Negative Regulation Of Biosynthetic Process Viral Process Erythrocyte Homeostasis Negative Regulation Of Nodal Signaling Pathway Oncogene-induced Cell Senescence Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Sister Chromatid Biorientation Myeloid Cell Homeostasis Negative Regulation Of Calcidiol 1-monooxygenase Activity
Tagcloud ?		133a bidirectional biphasic compatible concurrently datasets declining directionally e2f ets ets2 gabp hf insult interrelated kegg late microrna mirna miss myocyte nonfailing omnibus overlapping overrepresented repository rising transcripts undergo