EIF1AX

Gene Name		eukaryotic translation initiation factor 1A, X-linked
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Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	Translation Initiation Factor Activity Protein Binding Translation Factor Activity, Nucleic Acid Binding Poly(A) RNA Binding
	Biological Process	Translation Translational Initiation Gene Expression Cellular Protein Metabolic Process
Pathways		Ribosomal scanning and start codon recognition Translation initiation complex formation Formation of the ternary complex, and subsequently, the 43S complex GTP hydrolysis and joining of the 60S ribosomal subunit Translation Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Cap-dependent Translation Initiation L13a-mediated translational silencing of Ceruloplasmin expression
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: APP EIF2S1 EIF3C EIF5 EIF5B IKBKG IPO13
Entrez ID		1964
HPRD ID		02174
Ensembl ID		ENSG00000173674
Uniprot IDs		P47813
PDB IDs		1D7Q 3ZJY 4KZY 4KZZ
Enriched GO Terms of Interacting Partners?		Regulation Of Translational Initiation Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Translational Initiation Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Translation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Gene Expression Regulation Of Gene Expression Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Cellular Macromolecule Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Macromolecule Biosynthetic Process Intracellular Receptor Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Regulation Of Protein Phosphorylation Regulation Of Translational Initiation In Response To Stress Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Translation In Response To Stress Regulation Of Phosphorylation Biosynthetic Process Regulation Of Metabolic Process Cellular Copper Ion Homeostasis
Tagcloud ?		aggregated anaplastic atc braf cdkn1b cdkn2c ctnnb1 exclusive exome harbored hypermutator landscape mismatch mlh mlh1 mlh3 msh5 msh6 mutational mutually nf1 nf2 nras ontology pik3ca ret unresponsive ush2a v600e