EGR3

Description		early growth response 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Synapse
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Cell Migration Involved In Sprouting Angiogenesis Regulation Of Transcription By RNA Polymerase II Neuromuscular Synaptic Transmission Peripheral Nervous System Development Muscle Organ Development Circadian Rhythm Positive Regulation Of T Cell Differentiation In Thymus Endothelial Cell Chemotaxis Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Apoptotic Process Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II System Development
Pathways		NGF-stimulated transcription NGF-stimulated transcription
Drugs
Diseases
GWAS		Cataracts ( 34127677) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Novel Interacting Genes		1 novel interacting genes: BLK
Interacting Genes		1 interacting genes: SNCA
Entrez ID		1960
HPRD ID		03881
Ensembl ID		ENSG00000179388
Uniprot IDs		B4DH80 Q06889
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Secretion Positive Regulation Of Secretion By Cell Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Positive Regulation Of Protein Localization Dopamine Uptake Involved In Synaptic Transmission Response To Iron(II) Ion Regulation Of Chaperone-mediated Autophagy Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Oxidative Phosphorylation Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Dopamine Biosynthetic Process Negative Regulation Of Cellular Respiration Regulation Of Secretion By Cell Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber Catecholamine Uptake Dopamine Uptake Positive Regulation Of Inositol Phosphate Biosynthetic Process Regulation Of Secretion SNARE Complex Assembly Cellular Response To Epinephrine Stimulus Positive Regulation Of Receptor Recycling Regulation Of SNARE Complex Assembly Negative Regulation Of Microtubule Polymerization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway ATP Synthesis Coupled Electron Transport Synaptic Transmission, Dopaminergic Response To Epinephrine Positive Regulation Of Transport Positive Regulation Of Neurotransmitter Secretion Regulation Of Hydrogen Peroxide Metabolic Process Platelet Alpha Granule Membrane Dynein Complex Binding Synaptic Vesicle Priming Dopamine Transport
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