MEGF8

Gene Name		multiple EGF-like-domains 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Calcium Ion Binding Protein Binding
	Biological Process	Embryonic Heart Tube Morphogenesis Regulation Of Gene Expression Embryonic Limb Morphogenesis BMP Signaling Pathway Limb Morphogenesis Cell Migration Involved In Gastrulation Embryonic Skeletal System Morphogenesis Positive Regulation Of Axon Extension Involved In Axon Guidance Epiboly Involved In Gastrulation With Mouth Forming Second Embryonic Heart Tube Left/right Pattern Formation Left/right Pattern Formation Determination Of Heart Left/right Asymmetry Determination Of Digestive Tract Left/right Asymmetry Craniofacial Suture Morphogenesis Fasciculation Of Sensory Neuron Axon
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: ATN1 CACNA1A GFI1B
Entrez ID		1954
HPRD ID		10370
Ensembl ID		ENSG00000105429
Uniprot IDs		Q7Z7M0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cerebellar Molecular Layer Development Negative Regulation Of Biosynthetic Process Vestibular Nucleus Development Musculoskeletal Movement, Spinal Reflex Action Cerebellum Maturation Gamma-aminobutyric Acid Secretion Regulation Of Acetylcholine Secretion, Neurotransmission Rhythmic Synaptic Transmission Negative Regulation Of Cellular Metabolic Process Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Negative Regulation Of Hormone Biosynthetic Process Maintenance Of Cell Polarity Pons Development Toxin Metabolic Process Cerebellar Purkinje Cell Differentiation Cerebellar Purkinje Cell Layer Morphogenesis Reflex Behavioral Response To Pain Regulation Of Histone H3-K4 Methylation Neuromuscular Synaptic Transmission Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Hormone Biosynthetic Process Cerebellar Cortex Formation Neurotransmitter Metabolic Process Gamma-aminobutyric Acid Signaling Pathway Cell Differentiation In Hindbrain Calcium Ion Import Regulation Of Hormone Metabolic Process Cerebellar Purkinje Cell Layer Development Membrane Depolarization During Action Potential Central Nervous System Development Response To Pain Cerebellar Cortex Morphogenesis Synaptic Transmission, Glutamatergic Sulfur Amino Acid Metabolic Process Musculoskeletal Movement System Development Calcium Ion-dependent Exocytosis Anion Homeostasis Spinal Cord Motor Neuron Differentiation Cell Death Death Adult Walking Behavior Negative Regulation Of Transcription, DNA-templated Cerebellum Morphogenesis Receptor Clustering Negative Regulation Of Nucleic Acid-templated Transcription
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