DUSP9

Gene Name		dual specificity phosphatase 9
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity
	Biological Process	Inactivation Of MAPK Activity Protein Dephosphorylation JNK Cascade Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Type 2 diabetes ( 22961080 20581827)
Protein-protein Interactions		5 interactors: CDK4 GSK3B MAPK1 MAPK14 MAPK3
Entrez ID		1852
HPRD ID		02136
Ensembl ID		ENSG00000130829
Uniprot IDs		B2RAL9 Q99956
PDB IDs		2HXP 3LJ8
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Response To Heat Lipopolysaccharide-mediated Signaling Pathway Regulation Of Protein Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Kinase Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Regulation Of MAP Kinase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Golgi Inheritance Cellular Response To Heat Regulation Of Protein Phosphorylation MyD88-independent Toll-like Receptor Signaling Pathway Response To Abiotic Stimulus Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process MyD88-dependent Toll-like Receptor Signaling Pathway Caveolin-mediated Endocytosis Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Protein Phosphorylation Regulation Of Intracellular Transport Cell Cycle Vascular Endothelial Growth Factor Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Golgi Organization Toll-like Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Response To Heat Positive Regulation Of Macromolecule Biosynthetic Process Stress-activated MAPK Cascade Peptidyl-serine Phosphorylation Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cellular Response To Growth Factor Stimulus Activation Of MAPK Activity Chemotaxis Response To Growth Factor Regulation Of Early Endosome To Late Endosome Transport Activation Of Innate Immune Response Regulation Of MAPK Cascade
Tagcloud ?		1c asians besides cdc123 cdkal1 cdkn2a comprising confirming east ethnic ethnically fasting glis3 grk5 hans hba hnf1b kcnq1 loci nondiabetic novo pathophysiology rasgrp1 replication rs10886471 rs7403531 shed silico t2d