DUSP2

Gene Name		dual specificity phosphatase 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Tyrosine/threonine Phosphatase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Mitogen-activated Protein Kinase Binding
	Biological Process	Inactivation Of MAPK Activity Endoderm Formation Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: MAPK1 MAPK14
Entrez ID		1844
HPRD ID		04348
Ensembl ID		ENSG00000158050
Uniprot IDs		Q05923
PDB IDs		1M3G
Enriched GO Terms of Interacting Partners?		Lipopolysaccharide-mediated Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Peptidyl-serine Phosphorylation Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of MAPK Activity Activation Of Innate Immune Response Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Positive Regulation Of Innate Immune Response Platelet Activation P38MAPK Cascade Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Ras Protein Signal Transduction Neurotrophin Signaling Pathway MAPK Cascade Regulation Of Innate Immune Response Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity MAPK Import Into Nucleus Response To Lipopolysaccharide Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Molecule Of Bacterial Origin Regulation Of Golgi Inheritance Cellular Response To Lipid Blood Coagulation Hemostasis Regulation Of Intracellular Transport Positive Regulation Of MAPK Cascade Posttranscriptional Regulation Of Gene Expression Caveolin-mediated Endocytosis Positive Regulation Of Brown Fat Cell Differentiation Cytosine Metabolic Process
Tagcloud ?		3d amplifications belongs blocks bypass dimensional downstream dual erbb2 erk expressing hif hypoxia hypoxic indeed lapatinib maintain maintains mammary mek normoxic overexpression phosphatase positve rationale resistance reverses sufficient trametinib