DUSP2

Description		dual specificity phosphatase 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/threonine Phosphatase Activity Hydrolase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Mitogen-activated Protein Kinase Binding
	Biological Process	Endoderm Formation Protein Dephosphorylation Signal Transduction Negative Regulation Of MAPK Cascade
Pathways		RAF-independent MAPK1/3 activation Negative regulation of MAPK pathway
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: CSNK2A1 MAPK1 MAPK14 STAT1 USP7
Entrez ID		1844
HPRD ID		04348
Ensembl ID		ENSG00000158050
Uniprot IDs		Q05923
PDB IDs		1M3G
Enriched GO Terms of Interacting Partners?		Symbiont-mediated Disruption Of Host Cell PML Body Response To Nutrient Levels MAP Kinase Activity DNA Damage Response Negative Regulation Of Intracellular Signal Transduction Stress-activated MAPK Cascade Regulation Of Intracellular Signal Transduction Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Population Proliferation Regulation Of Intracellular Transport Lipopolysaccharide-mediated Signaling Pathway Protein Serine Kinase Activity Regulation Of Biological Quality Regulation Of Erythrocyte Differentiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Catabolic Process Regulation Of Protein Stability Cytokine-mediated Signaling Pathway Tumor Necrosis Factor-mediated Signaling Pathway Protein Serine/threonine Kinase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Cytokine Stimulus Regulation Of Signal Transduction Regulation Of DNA-templated Transcription Response To Stress Regulation Of RNA Biosynthetic Process Negative Regulation Of Signal Transduction Regulation Of DNA Metabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Kinase Activity Positive Regulation Of Metabolic Process Regulation Of Cellular Localization Regulation Of RNA Metabolic Process Cellular Response To Stress Negative Regulation Of Signaling Response To Peptide Response To Cytokine Regulation Of Cell Communication Negative Regulation Of Cell Communication Cellular Response To Tumor Necrosis Factor Regulation Of Signaling DNA Damage Checkpoint Signaling Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Regulation Of Cell Population Proliferation Positive Regulation Of Myeloid Cell Differentiation PML Body Regulation Of Telomere Maintenance Kinase Activity
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