DPP6

Gene Name		dipeptidyl-peptidase 6
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Serine-type Peptidase Activity Dipeptidyl-peptidase Activity
	Biological Process	Proteolysis Neuronal Action Potential Positive Regulation Of Potassium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 18987618 18057069 18084291) Pancreatic cancer ( 20686608) QT interval ( 23534349) Tardive dyskinesia ( 21826085)
Protein-protein Interactions		1 interactors: PRNP
Entrez ID		1804
HPRD ID		00525
Ensembl ID		ENSG00000130226
Uniprot IDs		E9PF59 P42658
PDB IDs		1XFD
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Copper Ion Negative Regulation Of Calcium-mediated Signaling Negative Regulation Of Interleukin-17 Production Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Activated T Cell Proliferation Negative Regulation Of Interleukin-2 Production Cellular Copper Ion Homeostasis Negative Regulation Of T Cell Receptor Signaling Pathway Response To Copper Ion Copper Ion Homeostasis Negative Regulation Of Interferon-gamma Production Regulation Of Activated T Cell Proliferation Regulation Of Potassium Ion Transmembrane Transport Regulation Of Calcium-mediated Signaling Regulation Of T Cell Receptor Signaling Pathway Response To Cadmium Ion Regulation Of Potassium Ion Transport Negative Regulation Of T Cell Proliferation Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Leukocyte Proliferation Regulation Of Interferon-gamma Production Negative Regulation Of T Cell Activation Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Metal Ion Negative Regulation Of Lymphocyte Activation Negative Regulation Of Cell-cell Adhesion Cellular Response To Inorganic Substance Regulation Of T Cell Proliferation Cell Cycle Arrest Transition Metal Ion Homeostasis Negative Regulation Of Leukocyte Activation Negative Regulation Of Cell Adhesion Negative Regulation Of Cytokine Production Protein Homooligomerization Learning Or Memory Cognition Regulation Of T Cell Activation Negative Regulation Of Protein Phosphorylation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Metal Ion Regulation Of Cell-cell Adhesion Negative Regulation Of Immune System Process Axon Guidance Regulation Of Lymphocyte Activation Negative Regulation Of Phosphorylation Cellular Metal Ion Homeostasis
Tagcloud ?		accelerate accelerates associates auxiliary bridges c349 c356 c465 c468 channel cysteine dipeptidyl disulfide enhance enhancement entire export folding gated kinetics kv4 peptidase potently remarkable rich stabilization structurally transmembrane voltage