DOCK3

Gene Name		dedicator of cytokinesis 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding SH3 Domain Binding
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Height ( 20881960)
Protein-protein Interactions		5 interactors: CALM1 CRK KHDRBS1 PSEN1 PSEN2
Entrez ID		1795
HPRD ID		10341
Ensembl ID		ENSG00000088538
Uniprot IDs		Q8IZD9
PDB IDs
Enriched GO Terms of Interacting Partners?		Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Amyloid Precursor Protein Catabolic Process Cell Activation Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Kinase Activity Membrane Protein Ectodomain Proteolysis Notch Receptor Processing Regulation Of Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Metabolic Process Neurotrophin Signaling Pathway Regulation Of Immune Response Regulation Of Epidermal Growth Factor-activated Receptor Activity Endoplasmic Reticulum Calcium Ion Homeostasis Immune Response-activating Cell Surface Receptor Signaling Pathway Dorsal/ventral Neural Tube Patterning Positive Regulation Of Coagulation Regulation Of Protein Phosphorylation Membrane Protein Proteolysis Negative Regulation Of Protein Phosphorylation Brain Morphogenesis Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Signaling Cell Surface Receptor Signaling Pathway Immune Response Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Phosphorylation Regulation Of Immune System Process Regulation Of Phosphorylation Thymus Development Neural Tube Patterning Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Metabolic Process T Cell Activation Involved In Immune Response Activation Of MAPKK Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Kinase Activity Positive Regulation Of Catalytic Activity Regulation Of Cellular Ketone Metabolic Process Regulation Of ERBB Signaling Pathway Somitogenesis Positive Regulation Of Transferase Activity
Tagcloud ?		apterous basket bsk counterpart cytokinesis dedicator discs dock1 dock11 driver drosophila duolink gal4 imaginal immunoblot jnk lacz ligation pannir pjnk proximity puckered rac1 spg split sponge thorax wing