TRIM60

Description		tripartite motif containing 60
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity SUMO-ubiquitin Ligase Activity
	Biological Process	Canonical NF-kappaB Signal Transduction Regulation Of Gene Expression Non-canonical NF-kappaB Signal Transduction Innate Immune Response Protein K63-linked Ubiquitination Negative Regulation Of Non-canonical NF-kappaB Signal Transduction
Pathways
Drugs
Diseases
GWAS		Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877)
Interacting Genes		2 interacting genes: CDC42 LNX1
Entrez ID		166655
HPRD ID		11502
Ensembl ID		ENSG00000176979
Uniprot IDs		Q495X7
PDB IDs
Enriched GO Terms of Interacting Partners?		Leading Edge Membrane Thioesterase Binding Positive Regulation Of Pinocytosis Apolipoprotein A-I Receptor Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Endothelin Receptor Signaling Pathway Involved In Heart Process Ubiquitin Protein Ligase Activity Neuron Fate Determination Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Establishment Of Golgi Localization Nervous System Development Neuropilin Signaling Pathway Postsynapse GBD Domain Binding Golgi Transport Complex Storage Vacuole Cell Junction Organization Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Positive Regulation Of Pseudopodium Assembly Endothelin Receptor Signaling Pathway Golgi Localization Cardiac Conduction System Development Establishment Of Epithelial Cell Apical/basal Polarity Cell Migration Involved In Heart Development Synapse Maturation Regulation Of Attachment Of Spindle Microtubules To Kinetochore Establishment Of Apical/basal Cell Polarity Dendritic Cell Migration Establishment Of Monopolar Cell Polarity GTP-dependent Protein Binding Heart Contraction Embryonic Heart Tube Development Dendritic Spine Morphogenesis Filopodium Assembly Establishment Or Maintenance Of Monopolar Cell Polarity Polarized Epithelial Cell Differentiation Positive Regulation Of Lamellipodium Assembly Spindle Midzone Nuclear Migration Nucleus Localization Heart Process Establishment Of Epithelial Cell Polarity Positive Regulation Of Filopodium Assembly Dendritic Spine Organization Phagocytosis, Engulfment System Development Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of Lamellipodium Organization Macrophage Differentiation
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