DECR1

Description		2,4-dienoyl-CoA reductase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Catalytic Complex
	Molecular Function	2,4-dienoyl-CoA Reductase (NADPH) Activity Oxidoreductase Activity Identical Protein Binding NADPH Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Positive Regulation Of Cold-induced Thermogenesis
Pathways		mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
Drugs		Nicotinamide adenine dinucleotide phosphate 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL
Diseases
GWAS		Blood protein levels ( 30072576)
Novel Interacting Genes		2 novel interacting genes: CLCN3 MMP16
Interacting Genes		2 interacting genes: APP HGS
Entrez ID		1666
HPRD ID		01959
Ensembl ID		ENSG00000104325
Uniprot IDs		Q16698
PDB IDs		1W6U 1W73 1W8D
Enriched GO Terms of Interacting Partners?		Early Endosome Membrane Early Endosome Membrane Invagination Lysosome Positive Regulation Of Reactive Oxygen Species Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Adult Locomotory Behavior Cell Surface Regulation Of Response To Calcium Ion Golgi Lumen Amylin Binding Positive Regulation Of Toll Signaling Pathway Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Recycling Endosome Endosome Endosome To Plasma Membrane Transport Vesicle Adult Behavior Positive Regulation Of Endothelin Production Regulation Of Reactive Oxygen Species Metabolic Process Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Chloride:proton Antiporter Activity ESCRT-0 Complex Locomotory Behavior Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Phagocytic Vesicle Lumen Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Negative Regulation Of Cell Volume Volume-sensitive Chloride Channel Activity Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity
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