KBTBD12

Name	kelch repeat and BTB domain containing 12
Structure
Interactors	1 interactors: CRYAA
GO Annotations	Cellular Component	Cytoplasm Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
GWAS	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143 ) Platelet count ( 32888494 )
Entrez ID	166348
HPRD ID	17001
Ensembl ID	ENSG00000187715
Uniprot IDs	Q3ZCT8
PDB IDs	7QZQ
GO Terms Enriched among Interactors ?	Tubulin Complex Assembly Response To UV-A Lens Fiber Cell Morphogenesis Structural Constituent Of Eye Lens Embryonic Eye Morphogenesis Apoptotic Process Involved In Morphogenesis Protein Refolding Embryonic Camera-type Eye Morphogenesis Lens Morphogenesis In Camera-type Eye Apoptotic Process Involved In Development Lens Development In Camera-type Eye Eye Morphogenesis Negative Regulation Of Intracellular Transport Sensory Organ Morphogenesis Response To Heat Camera-type Eye Development Response To Hydrogen Peroxide Unfolded Protein Binding Embryonic Organ Morphogenesis Eye Development Positive Regulation Of Cell Growth Structural Molecule Activity Visual Perception Sensory Organ Development Response To UV Sensory Perception Of Light Stimulus Response To Reactive Oxygen Species Cell Morphogenesis Response To Temperature Stimulus Protein Folding Protein Stabilization Actin Filament Organization Positive Regulation Of Growth Regulation Of Intracellular Transport Mitochondrion Organization