DDT

Description		D-dopachrome tautomerase
Image
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Extracellular Exosome
	Molecular Function	Dopachrome Isomerase Activity Cytokine Receptor Binding Lyase Activity D-dopachrome Decarboxylase Activity Phenylpyruvate Tautomerase Activity
	Biological Process	Negative Regulation Of Macrophage Chemotaxis Positive Regulation Of Tumor Necrosis Factor Production Melanin Biosynthetic Process Positive Regulation Of Inflammatory Response Positive Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases
GWAS		Liver enzyme levels (gamma-glutamyl transferase) ( 22001757)
Novel Interacting Genes		1 novel interacting genes: ADORA2A
Interacting Genes
Entrez ID		1652
HPRD ID		04126
Ensembl ID		ENSG00000099977
Uniprot IDs		B5MC82 P30046 Q53Y51
PDB IDs		1DPT 3KAN 4Q3F 6C5F 7MRU 7MRV 7MSE 7MW7 8DBB 8VDY 8VFK 8VFL 8VFN 8VFO 8VFW 8VG5 8VG7 8VG8 9BB0
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neurotransmitter Secretion Regulation Of Norepinephrine Secretion Regulation Of Acetylcholine Secretion, Neurotransmission Positive Regulation Of Circadian Rhythm Purinergic Nucleotide Receptor Signaling Pathway Regulation Of Urine Volume Synaptic Transmission, Dopaminergic Prepulse Inhibition Inhibitory Postsynaptic Potential Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Positive Regulation Of Synaptic Transmission, Cholinergic Positive Regulation Of Urine Volume Synaptic Transmission, Cholinergic Positive Regulation Of Long-term Synaptic Potentiation Astrocyte Activation G Protein-coupled Adenosine Receptor Activity Asymmetric Synapse Regulation Of Glutamate Secretion Positive Regulation Of Glutamate Secretion Axolemma Alpha-actinin Binding Positive Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of Amino Acid Transport Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Circadian Sleep/wake Cycle Response To Caffeine G Protein-coupled Adenosine Receptor Signaling Pathway Negative Regulation Of Vascular Permeability Positive Regulation Of Acetylcholine Secretion, Neurotransmission Type 5 Metabotropic Glutamate Receptor Binding Positive Regulation Of Behavior Eating Behavior Response To Amphetamine Positive Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Synaptic Transmission, GABAergic Presynaptic Active Zone Regulation Of Catecholamine Secretion Presynaptic Modulation Of Chemical Synaptic Transmission Blood Circulation Regulation Of Long-term Synaptic Potentiation Synaptic Transmission, Glutamatergic Response To Amine Regulation Of Vascular Permeability Negative Regulation Of Alpha-beta T Cell Activation Cellular Defense Response Membrane Depolarization Vasodilation Excitatory Postsynaptic Potential Regulation Of Mitochondrial Membrane Potential Regulation Of Synaptic Transmission, Glutamatergic
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