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DENND2C

Description DENN domain containing 2C
Image No pdb structure
GO Annotations Cellular Component
  • Nucleoplasm
Molecular Function
  • Guanyl-nucleotide Exchange Factor Activity
  • Protein Binding
Biological Process
Pathways
  • RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS
  • Autism ( 24189344)
  • Mean platelet volume ( 32888494)
  • Platelet distribution width ( 32888494)
  • Type 2 diabetes ( 30297969)
Interacting Genes 1 interacting genes: YES1
Entrez ID 163259
HPRD ID 13425
Ensembl ID ENSG00000175984
Uniprot IDs Q68D51
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Phosphotyrosine Residue Binding
  • Regulation Of Vascular Permeability
  • Response To Platelet-derived Growth Factor
  • T Cell Costimulation
  • Fc-gamma Receptor Signaling Pathway
  • Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
  • Cellular Response To Platelet-derived Growth Factor Stimulus
  • Non-membrane Spanning Protein Tyrosine Kinase Activity
  • Negative Regulation Of Inflammatory Response To Antigenic Stimulus
  • Fc Receptor Mediated Stimulatory Signaling Pathway
  • Ephrin Receptor Signaling Pathway
  • Fc Receptor Signaling Pathway
  • Cellular Response To Transforming Growth Factor Beta Stimulus
  • Cellular Response To Retinoic Acid
  • Response To Transforming Growth Factor Beta
  • Regulation Of D-glucose Transmembrane Transport
  • Actin Filament
  • Response To Retinoic Acid
  • Protein Tyrosine Kinase Activity
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