EID2

Description		EP300 interacting inhibitor of differentiation 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding SMAD Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transforming Growth Factor Beta Receptor Complex Assembly Muscle Organ Development Cell Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Population Proliferation Negative Regulation Of DNA-templated Transcription Negative Regulation Of SMAD Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS		Lead levels ( 26025379)
Interacting Genes		8 interacting genes: EID2B EP300 HDAC1 HDAC2 LINC00839 SMAD2 SMAD3 SMAD4
Entrez ID		163126
HPRD ID		16754
Ensembl ID		ENSG00000176396
Uniprot IDs		Q8N6I1
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Endoderm Development Regulation Of Cellular Response To Growth Factor Stimulus SMAD Protein Complex Heteromeric SMAD Protein Complex DNA-binding Transcription Factor Binding Positive Regulation Of Epithelial To Mesenchymal Transition Chromatin Binding Animal Organ Morphogenesis Response To Transforming Growth Factor Beta Transcription Regulator Complex I-SMAD Binding Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Response To Growth Factor Regulation Of Epithelial To Mesenchymal Transition SMAD Protein Signal Transduction Negative Regulation Of RNA Metabolic Process R-SMAD Binding Activin Receptor Signaling Pathway Anatomical Structure Formation Involved In Morphogenesis Negative Regulation Of Nucleobase-containing Compound Metabolic Process NF-kappaB Binding Regulation Of Cell Differentiation Epithelial Cell Differentiation Positive Regulation Of Cell Differentiation Embryonic Morphogenesis Anterior/posterior Pattern Specification Protein Lysine Delactylase Activity Fungiform Papilla Formation Activin Responsive Factor Complex Paraxial Mesoderm Morphogenesis Negative Regulation Of Developmental Process Regulation Of Cell Fate Commitment Protein Decrotonylase Activity Histone Decrotonylase Activity Gastrulation Transcription Corepressor Binding Transcription Coactivator Binding Chromatin Embryonic Digit Morphogenesis Hair Follicle Placode Formation Mesoderm Morphogenesis Embryonic Pattern Specification Cellular Response To Transforming Growth Factor Beta Stimulus Pericardium Development Positive Regulation Of Gene Expression
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