DGKG

Description		diacylglycerol kinase gamma
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding ATP-dependent Diacylglycerol Kinase Activity Calcium Ion Binding ATP Binding Zinc Ion Binding Lipid Binding Kinase Activity Transferase Activity Metal Ion Binding
	Biological Process	Lipid Metabolic Process Phosphatidic Acid Biosynthetic Process Signal Transduction Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Glycerolipid Metabolic Process Lipid Phosphorylation Regulation Of Dendrite Development Negative Regulation Of Phospholipase C/protein Kinase C Signal Transduction
Pathways		Effects of PIP2 hydrolysis
Drugs		Phosphatidyl serine alpha-Tocopherol succinate
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Apolipoprotein A1 levels ( 32203549) Body mass index ( 19079260 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Chronotype ( 30696823) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 33627673) Gut microbiota (functional units) ( 27694959) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Intraocular pressure ( 29235454 29617998 29785010 30054594) Methadone dose in opioid dependence ( 28115739) Morning person ( 30696823) Neutrophil count ( 32888494) Response to citalopram or escitalopram and depression ( 27622933) Weight ( 28552196 19079260) White blood cell count ( 32888494)
Interacting Genes		1 interacting genes: ZEB2
Entrez ID		1608
HPRD ID		03510
Ensembl ID		ENSG00000058866
Uniprot IDs		P49619
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Melanosome Organization Regulation Of Myofibroblast Contraction Mammillary Axonal Complex Development Regulation Of Myofibroblast Cell Apoptotic Process Positive Regulation Of Lens Fiber Cell Differentiation Positive Regulation Of Myofibroblast Contraction Phosphatase Regulator Activity Regulation Of Melanocyte Differentiation Corticospinal Tract Morphogenesis Melanocyte Migration Myofibroblast Differentiation Corpus Callosum Morphogenesis Positive Regulation Of Pigment Cell Differentiation Positive Regulation Of Melanocyte Differentiation Fibroblast Activation Positive Regulation Of Developmental Pigmentation Regulation Of Lens Fiber Cell Differentiation Regulation Of Blood-brain Barrier Permeability Positive Regulation Of Melanin Biosynthetic Process Response To Oxygen-glucose Deprivation Regulation Of Melanin Biosynthetic Process Regulation Of Developmental Pigmentation Cell Proliferation In Forebrain Negative Regulation Of Fibroblast Migration Developmental Pigmentation Collateral Sprouting Astrocyte Activation Contractile Actin Filament Bundle Assembly Stress Fiber Assembly Central Nervous System Projection Neuron Axonogenesis R-SMAD Binding Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Central Nervous System Neuron Axonogenesis Epithelial Cell Migration Endothelial Cell Proliferation Regulation Of Fibroblast Migration Pyroptotic Inflammatory Response Somitogenesis Regulation Of Vascular Permeability Pigmentation Segmentation Neural Crest Cell Migration Mesenchymal Cell Migration Actin Filament Bundle Assembly Positive Regulation Of Epithelial Cell Differentiation Actin Filament Bundle Organization Hippocampus Development Positive Regulation Of Axonogenesis Endothelial Cell Migration Neural Tube Closure
Tagcloud ?