TMTC3

Description		transmembrane O-mannosyltransferase targeting cadherins 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane
	Molecular Function	Mannosyltransferase Activity Dolichyl-phosphate-mannose-protein Mannosyltransferase Activity Protein Binding Transferase Activity
	Biological Process	Protein Glycosylation Response To Endoplasmic Reticulum Stress Protein O-linked Glycosylation Via Mannose Regulation Of Macromolecule Metabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		1 interacting genes: DAB1
Entrez ID		160418
HPRD ID		10243
Ensembl ID		ENSG00000139324
Uniprot IDs		A8K321 Q6ZXV5
PDB IDs
Enriched GO Terms of Interacting Partners?		Lateral Motor Column Neuron Migration Cerebellum Structural Organization Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Spinal Cord Motor Neuron Migration Radial Glia Guided Migration Of Purkinje Cell Radial Glia-guided Pyramidal Neuron Migration Ventral Spinal Cord Development Negative Regulation Of Astrocyte Differentiation Cell Migration In Hindbrain Golgi Localization Reelin-mediated Signaling Pathway Motor Neuron Migration Layer Formation In Cerebral Cortex Anatomical Structure Arrangement Cerebral Cortex Radially Oriented Cell Migration Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Astrocyte Differentiation Regulation Of Astrocyte Differentiation Adult Walking Behavior Cerebral Cortex Cell Migration Negative Regulation Of Glial Cell Differentiation Negative Regulation Of Receptor Signaling Pathway Via STAT Regulation Of Synapse Maturation Walking Behavior Telencephalon Cell Migration Negative Regulation Of Gliogenesis Dendrite Development Forebrain Cell Migration Negative Regulation Of Axonogenesis Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Glial Cell Differentiation Hippocampus Development Cell Surface Receptor Signaling Pathway Via JAK-STAT Adult Locomotory Behavior Signaling Adaptor Activity Cell Surface Receptor Signaling Pathway Via STAT Positive Regulation Of Neuron Differentiation Regulation Of Gliogenesis Glial Cell Differentiation Negative Regulation Of Neuron Projection Development Intracellular Membrane-bounded Organelle Negative Regulation Of Nervous System Development Central Nervous System Neuron Differentiation Regulation Of Axonogenesis Negative Regulation Of Neurogenesis Neuron Migration Adult Behavior Axonogenesis Negative Regulation Of Cell Projection Organization Locomotory Behavior
Tagcloud ?