VPS13B

Description		vacuolar protein sorting 13 homolog B
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Membrane Lysosome Lysosomal Membrane Endosome Golgi Apparatus Membrane Cytoplasmic Vesicle Early Endosome Membrane Trans-Golgi Network Membrane Cis-Golgi Network Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Recycling Endosome Membrane
	Molecular Function	Lipid Binding Phosphatidylinositol-3-phosphate Binding
	Biological Process	Acrosome Assembly Lipid Transport Golgi Organization Nervous System Development Central Nervous System Development Brain Development Muscle Organ Development Memory Vesicle-mediated Transport Dentate Gyrus Development Neuron Projection Development Slow Endocytic Recycling Social Behavior Multicellular Organism Growth Maintenance Of Lens Transparency Head Morphogenesis Adipose Tissue Development Golgi Reassembly
Pathways
Drugs
Diseases		Cohen syndrome
GWAS		Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903) Glucose homeostasis traits ( 25524916) Heel bone mineral density ( 30598549) Intake of total sugars ( 31005972) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Nose morphology ( 29921221 33593615) Red blood cell count ( 32888494)
Interacting Genes		1 interacting genes: USP7
Entrez ID		157680
HPRD ID		06379
Ensembl ID		ENSG00000132549
Uniprot IDs		Q7Z7G8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Retrograde Transport, Endosome To Golgi Monoubiquitinated Protein Deubiquitination DNA Alkylation Repair Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Regulation Of Telomere Capping Negative Regulation Of Gluconeogenesis K48-linked Deubiquitinase Activity Deubiquitinase Activity Nucleotide-excision Repair Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of TORC1 Signaling Regulation Of Gluconeogenesis Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Cysteine-type Endopeptidase Activity Negative Regulation Of Autophagy Negative Regulation Of Small Molecule Metabolic Process P53 Binding Cysteine-type Deubiquitinase Activity Autophagosome Organization Protein Deubiquitination Protein Modification By Small Protein Removal Autophagosome Assembly Regulation Of TORC1 Signaling Regulation Of Circadian Rhythm Negative Regulation Of TOR Signaling TOR Signaling Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Protein Catabolic Process Regulation Of Telomere Maintenance Regulation Of Glucose Metabolic Process PML Body Cysteine-type Peptidase Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Regulation Of TOR Signaling Vacuole Organization Negative Regulation Of Gene Expression, Epigenetic Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Autophagy Regulation Of DNA-binding Transcription Factor Activity Regulation Of Proteasomal Protein Catabolic Process Protein Stabilization Regulation Of Chromosome Organization
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