PLEKHG4B

Description		pleckstrin homology and RhoGEF domain containing G4B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Basal Plasma Membrane Membrane Extrinsic Component Of Membrane Anchoring Junction
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Axon Guidance Regulation Of Small GTPase Mediated Signal Transduction Cell-cell Adhesion
Pathways		CDC42 GTPase cycle
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 27611488) Face memory ( 31596458)
Interacting Genes		4 interacting genes: CDC42 FHL3 GLRX3 KPNA4
Entrez ID		153478
HPRD ID		13900
Ensembl ID		ENSG00000153404
Uniprot IDs		A0AAK2PKJ8 Q96PX9
PDB IDs
Enriched GO Terms of Interacting Partners?		Leading Edge Membrane Positive Regulation Of Pseudopodium Assembly Endothelin Receptor Signaling Pathway Thioesterase Binding Regulation Of Attachment Of Spindle Microtubules To Kinetochore Actin Filament-based Process Establishment Of Apical/basal Cell Polarity Positive Regulation Of Pinocytosis Dendritic Cell Migration Apolipoprotein A-I Receptor Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Golgi Localization Establishment Of Monopolar Cell Polarity GTP-dependent Protein Binding Heart Contraction Endothelin Receptor Signaling Pathway Involved In Heart Process Cardiac Conduction System Development Embryonic Heart Tube Development Focal Adhesion Neuron Fate Determination Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Dendritic Spine Morphogenesis Dendrite Establishment Of Golgi Localization Actin Cytoskeleton Organization Establishment Of Epithelial Cell Apical/basal Polarity Filopodium Assembly Establishment Or Maintenance Of Monopolar Cell Polarity Neuropilin Signaling Pathway GBD Domain Binding Golgi Transport Complex Storage Vacuole Cell Migration Involved In Heart Development Polarized Epithelial Cell Differentiation Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Z Disc Positive Regulation Of Hippo Signaling NLS-bearing Protein Import Into Nucleus Dopamine Secretion Catecholamine Secretion Nuclear Import Signal Receptor Activity Nuclear Localization Sequence Binding Dopamine Transport NLS-dependent Protein Nuclear Import Complex Iron-sulfur Cluster Assembly Complex Iron-sulfur Cluster Assembly [2Fe-2S] Cluster Assembly Spindle Midzone Regulation Of The Force Of Heart Contraction
Tagcloud ?