ZNF827

Description		zinc finger protein 827
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Chromosome Ribonucleoprotein Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding NuRD Complex Binding
	Biological Process	Telomere Maintenance Chromatin Remodeling Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Establishment Of Protein Localization To Telomere Negative Regulation Of Shelterin Complex Assembly
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 34315874 33547301 33339817) Alanine transaminase levels ( 29403010) Appendicular lean mass ( 33097823) Aspartate aminotransferase levels ( 34315874 33547301 33339817 29403010) Carboplatin disposition in epthelial ovarian cancer ( 29367611) Coronary artery disease ( 33020668 29212778) Dental caries ( 23064961) Gamma glutamyl transferase levels ( 33339817 29403010) Gamma glutamyl transpeptidase ( 21909109) Gut microbiota relative abundance (Dorea) ( 33208821) Heel bone mineral density ( 30598549 28869591) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757 33972514) Malaria ( 31844061) Prostate-specific antigen levels ( 28139693) Pulse pressure ( 27841878 30578418) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Reticulocyte fraction of red cells ( 32888494) Serum alkaline phosphatase levels ( 33547301) Severe skin toxicity response to cetuximab in colorectal cancer ( 30557370) Systolic blood pressure ( 27841878) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		3 interacting genes: MESD PPP1CA VHL
Entrez ID		152485
HPRD ID		14095
Ensembl ID		ENSG00000151612
Uniprot IDs		B3KSR1 H0Y9M2 Q17R98
PDB IDs		5XXQ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation RNA Polymerase II Promoter Clearance Regulation Of Glycogen Catabolic Process Regulation Of Wnt Signaling Pathway Protein Stabilization Positive Regulation Of Termination Of DNA-templated Transcription Glycogen Granule Positive Regulation Of Termination Of RNA Polymerase II Transcription Regulation Of Protein Stability PTW/PP1 Phosphatase Complex RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Transcription Elongation Factor Activity Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Double-strand Break Repair Via Alternative Nonhomologous End Joining Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Receptor Clustering Telomere Maintenance In Response To DNA Damage Protein Phosphatase Type 1 Complex Positive Regulation Of Glycogen Biosynthetic Process Regulation Of Receptor Clustering Transition Metal Ion Binding Cadherin Binding Involved In Cell-cell Adhesion Response To Lead Ion Entrainment Of Circadian Clock By Photoperiod Regulation Of Translation In Response To Stress Regulation Of Cellular Response To Hypoxia Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Protein Serine/threonine Kinase Binding Protein Phosphatase 1 Binding Photoperiodism Regulation Of Glycogen Biosynthetic Process Entrainment Of Circadian Clock Amyloid Fibril Formation Negative Regulation Of Receptor Signaling Pathway Via STAT Protein Localization To Cell Surface Low-density Lipoprotein Particle Receptor Binding Regulation Of Signal Transduction Positive Regulation Of Protein-containing Complex Disassembly Ribonucleoprotein Complex Binding Regulation Of Glycogen Metabolic Process Positive Regulation Of Glucose Metabolic Process Transcription Elongation By RNA Polymerase II Regulation Of Cell Communication Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
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