CMTM8

Description		CKLF like MARVEL transmembrane domain containing 8
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Cytoplasm Membrane
	Molecular Function	Cytokine Activity Protein Binding Structural Constituent Of Myelin Sheath
	Biological Process	Chemotaxis Signal Transduction Myelination
Pathways
Drugs
Diseases
GWAS		Diabetic retinopathy in type 2 diabetes ( 33607655) Height ( 28270201) HIV-1 viral setpoint ( 22174851) Periodontal disease-related phenotype (Socransky) ( 24347629) Urinary magnesium excretion ( 31993563)
Interacting Genes		4 interacting genes: AKT1 EGFR KRTAP1-3 TMEM14B
Entrez ID		152189
HPRD ID		06989
Ensembl ID		ENSG00000170293
Uniprot IDs		Q8IZV2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of G1/S Transition Of Mitotic Cell Cycle Response To UV-A Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Peptidyl-serine Phosphorylation Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Epidermal Growth Factor Stimulus Response To Epidermal Growth Factor Regulation Of Cell Cycle Phase Transition Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Mitotic Cell Cycle Positive Regulation Of Protein Localization To Cell Periphery ERBB Signaling Pathway Positive Regulation Of Protein Localization To Membrane Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Mitotic Cell Cycle Phase Transition Kinase Binding Regulation Of TRNA Methylation Multivesicular Body, Internal Vesicle Lumen Positive Regulation Of Cell Cycle Phase Transition Regulation Of Protein Localization To Plasma Membrane Cell Population Proliferation Regulation Of Cell Cycle Process Positive Regulation Of Mitotic Cell Cycle Regulation Of Protein Localization To Cell Periphery Response To UV Negative Regulation Of Protein Localization To Lysosome Shc-EGFR Complex Embryonic Organ Development Positive Regulation Of Cell Growth Positive Regulation Of Protein Localization To Endoplasmic Reticulum Response To Insulin-like Growth Factor Stimulus Mammalian Oogenesis Stage TRNA (guanine-N7)-methylation Regulation Of Protein Localization To Membrane Cellular Response To Rapamycin Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Endodeoxyribonuclease Activity Positive Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Receptor Activity Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Establishment Of Protein Localization To Membrane Positive Regulation Of Epithelial Cell Proliferation TORC2 Complex Binding Positive Regulation Of Deoxyribonuclease Activity Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Regulation Of Cell Cycle
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