SPICE1

Description		spindle and centriole associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Spindle Cytoskeleton Plasma Membrane Ciliary Basal Body
	Molecular Function	Protein Binding
	Biological Process	Regulation Of Centriole Replication Cell Division Metaphase Chromosome Alignment Mitotic Spindle Assembly
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Interacting Genes		2 interacting genes: KDM1A STXBP1
Entrez ID		152185
HPRD ID		11242
Ensembl ID		ENSG00000163611
Uniprot IDs		Q8N0Z3
PDB IDs
Enriched GO Terms of Interacting Partners?		Axon Target Recognition Developmental Maturation Extrinsic Component Of Presynaptic Membrane Presynaptic Dense Core Vesicle Exocytosis Positive Regulation Of Vesicle Docking Positive Regulation Of Glutamate Secretion, Neurotransmission Negative Regulation Of Synaptic Transmission, GABAergic Regulation Of Acrosomal Vesicle Exocytosis Protein Demethylase Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Platelet Degranulation Regulation Of Glutamate Secretion, Neurotransmission MRF Binding Neuronal Dense Core Vesicle Exocytosis Response To Fungicide Guanine Metabolic Process Synaptic Vesicle Maturation Dense Core Granule Exocytosis Histone H3K4 Demethylase Activity Calcium Ion-regulated Exocytosis Of Neurotransmitter Positive Regulation Of Neurotransmitter Secretion Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Negative Regulation Of Cellular Component Organization Regulation Of SNARE Complex Assembly Secretory Granule Localization Platelet Alpha Granule Regulation Of Synaptic Vesicle Priming SNARE Complex Assembly Positive Regulation Of Calcium Ion-dependent Exocytosis Protein-containing Complex Regulation Of Glutamate Secretion Negative Regulation Of Apoptotic Process Parallel Fiber To Purkinje Cell Synapse Positive Regulation Of Glutamate Secretion Phospholipase Binding Positive Regulation Of Amino Acid Transport Long-term Synaptic Depression Positive Regulation Of Mast Cell Degranulation Presynaptic Active Zone Cytoplasmic Component Syntaxin-1 Binding Synaptic Vesicle Priming Histone H3K9 Demethylase Activity Purine Nucleobase Metabolic Process Positive Regulation Of Cell Size Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Histone Demethylase Activity Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
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