UPP2

Gene Name		uridine phosphorylase 2
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Gene Ontology Annotations	Cellular Component	Cytosol Type III Intermediate Filament
	Molecular Function	Uridine Phosphorylase Activity
	Biological Process	Pyrimidine Nucleobase Metabolic Process Nucleoside Metabolic Process Nucleotide Catabolic Process Pyrimidine Nucleoside Salvage UMP Salvage Small Molecule Metabolic Process Uridine Metabolic Process Pyrimidine Nucleoside Catabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways		Pyrimidine catabolism Pyrimidine salvage reactions Pyrimidine metabolism Metabolism of nucleotides
Drugs
Diseases
GWAS		P-tau181p ( 20932310)
Protein-protein Interactions		2 interactors: SIAH1 VIM
Entrez ID		151531
HPRD ID		15627
Ensembl ID		ENSG00000007001
Uniprot IDs		O95045
PDB IDs		2XRF 3P0E 3P0F
Enriched GO Terms of Interacting Partners?		Bergmann Glial Cell Differentiation Intermediate Filament Organization Lens Fiber Cell Development Apoptotic Process Astrocyte Development Programmed Cell Death Protein Destabilization Cell Death Death Muscle Filament Sliding Actin-myosin Filament Sliding Lens Fiber Cell Differentiation Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Movement Of Cell Or Subcellular Component Generation Of Neurons SMAD Protein Signal Transduction Neuron Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Neurogenesis Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Actin Filament-based Movement Neuron Death Cell Development Execution Phase Of Apoptosis Lens Development In Camera-type Eye Glial Cell Development Nervous System Development Negative Regulation Of Neuron Projection Development
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