ASPRV1

Description		aspartic peptidase retroviral like 1
Image		No pdb structure
GO Annotations	Cellular Component	Membrane
	Molecular Function	Aspartic-type Endopeptidase Activity Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Protein Processing Skin Development
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181)
Interacting Genes		2 interacting genes: CDKN2A UCHL5
Entrez ID		151516
HPRD ID		08683
Ensembl ID		ENSG00000293615
Uniprot IDs		Q53RT3
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Regulation Of Ubiquitin-dependent Protein Catabolic Process Ligase Inhibitor Activity Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Proteolysis Senescence-associated Heterochromatin Focus Negative Regulation Of Catabolic Process Negative Regulation Of Immature T Cell Proliferation In Thymus Apoptotic Process Involved In Mammary Gland Involution Negative Regulation Of Ubiquitin Protein Ligase Activity Mitochondrial Depolarization Oncogene-induced Cell Senescence Positive Regulation Of Apoptotic Process Involved In Development Somatic Stem Cell Division Negative Regulation Of Immature T Cell Proliferation Protein Localization To Nucleolus Negative Regulation Of Cyclin-dependent Protein Kinase Activity Positive Regulation Of Apoptotic Process Involved In Morphogenesis MDM2/MDM4 Family Protein Binding Regulation Of Mammary Gland Epithelial Cell Proliferation Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Replicative Senescence Ubiquitin Ligase Inhibitor Activity Regulation Of Immature T Cell Proliferation In Thymus Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Metabolic Process Positive Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of T Cell Differentiation In Thymus Regulation Of Cellular Response To Stress Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Sumoylation Regulation Of DNA Strand Elongation Ino80 Complex Forebrain Morphogenesis Positive Regulation Of Telomere Maintenance In Response To DNA Damage Lateral Ventricle Development Nuclear Body Organization Positive Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of B Cell Proliferation Proteasome Binding SUMO Transferase Activity Post-translational Protein Modification
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