DCST1

Description		DC-STAMP domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Plasma Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Immune System Process Ubiquitin-dependent Protein Catabolic Process Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Protein Ubiquitination Sperm-egg Recognition Innate Immune Response Negative Regulation Of Type I Interferon-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 29782485) Prostate cancer ( 23535732) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		1 interacting genes: TP53
Entrez ID		149095
HPRD ID		08733
Ensembl ID		ENSG00000163357
Uniprot IDs		B4DXB8 B4DXE3 Q5T197
PDB IDs
Enriched GO Terms of Interacting Partners?		Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Histone Deacetylase Regulator Activity Negative Regulation Of Pentose-phosphate Shunt Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Response To Actinomycin D T Cell Proliferation Involved In Immune Response Negative Regulation Of Helicase Activity Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of G1 To G0 Transition Regulation Of G1 To G0 Transition Glucose Catabolic Process To Lactate Via Pyruvate Glial Cell Apoptotic Process Cellular Response To UV-C Germ Cell Nucleus Cellular Response To Actinomycin D ATP-dependent DNA/DNA Annealing Activity B Cell Lineage Commitment Regulation Of Pentose-phosphate Shunt Mitochondrial DNA Repair Bone Marrow Development Stress-induced Premature Senescence Regulation Of NADP Metabolic Process Negative Regulation Of MiRNA Processing Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Cellular Senescence Negative Regulation Of MiRNA-mediated Gene Silencing Regulation Of MiRNA Processing Regulation Of Thymocyte Apoptotic Process Thymocyte Apoptotic Process Negative Regulation Of ATP-dependent Activity ER Overload Response Mitotic G1 DNA Damage Checkpoint Signaling MDM2/MDM4 Family Protein Binding TFIID-class Transcription Factor Complex Binding Replicative Senescence Positive Regulation Of Programmed Necrotic Cell Death Type II Interferon-mediated Signaling Pathway Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Cellular Response To Antibiotic Negative Regulation Of Mitophagy Necroptotic Process General Transcription Initiation Factor Binding Regulation Of Regulatory NcRNA Processing Positive Regulation Of T Cell Apoptotic Process Striated Muscle Cell Apoptotic Process
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