SAMD8

Gene Name		sterile alpha motif domain containing 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Molecular_function Transferase Activity
	Biological Process	Sphingomyelin Biosynthetic Process Ceramide Biosynthetic Process Regulation Of Ceramide Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: TGFBR1
Entrez ID		142891
HPRD ID		18014
Ensembl ID		ENSG00000156671
Uniprot IDs		Q96LT4
PDB IDs
Enriched GO Terms of Interacting Partners?		Parathyroid Gland Development Endothelial Cell Activation Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of SMAD Protein Import Into Nucleus Germ Cell Migration Pharyngeal System Development Response To Cholesterol Negative Regulation Of Chondrocyte Differentiation Cardiac Epithelial To Mesenchymal Transition Activin Receptor Signaling Pathway Negative Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cartilage Development Positive Regulation Of Filopodium Assembly Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Filopodium Assembly Peptidyl-threonine Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Artery Morphogenesis Epithelial To Mesenchymal Transition Regulation Of Epithelial To Mesenchymal Transition Thymus Development Collagen Fibril Organization Positive Regulation Of Endothelial Cell Proliferation Artery Development Embryonic Cranial Skeleton Morphogenesis Activation Of MAPKK Activity Regulation Of Chondrocyte Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Protein Kinase B Signaling Neuron Fate Commitment Endothelial Cell Migration Regulation Of Endothelial Cell Proliferation Regulation Of Cartilage Development Positive Regulation Of Protein Import Into Nucleus Lens Development In Camera-type Eye Epithelial Cell Migration Epithelium Migration Blastocyst Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Palate Development Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Mesenchymal Cell Development Regulation Of Cell Projection Assembly Peptidyl-serine Phosphorylation Positive Regulation Of Cell Growth Embryonic Skeletal System Morphogenesis
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