TRPM6

Description		transient receptor potential cation channel subfamily M member 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Membrane Apical Plasma Membrane Brush Border Membrane
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Monoatomic Ion Channel Activity Monoatomic Cation Channel Activity Calcium Channel Activity Protein Binding ATP Binding Calcium Ion Transmembrane Transporter Activity Magnesium Ion Transmembrane Transporter Activity Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Response To Toxic Substance Metal Ion Transport Monoatomic Ion Transmembrane Transport Protein Tetramerization Transmembrane Transport Calcium Ion Transmembrane Transport Monoatomic Cation Transmembrane Transport Magnesium Ion Transmembrane Transport
Pathways		TRP channels
Drugs
Diseases
GWAS		Annualised percent change of cerebrospinal fluid AB1-42 levels ( 31370031) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Femur bone mineral density x serum urate levels interaction ( 34046847) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Magnesium levels ( 20700443 26058915) Metabolite levels ( 23823483) Pre-treatment viral load in HIV-1 infection ( 31219150) Prepulse inhibition of the startle response ( 31596458) Urinary magnesium-to-creatinine ratio ( 29093028)
Interacting Genes		1 interacting genes: TRPM7
Entrez ID		140803
HPRD ID		06112
Ensembl ID		ENSG00000119121
Uniprot IDs		Q9BX84
PDB IDs
Enriched GO Terms of Interacting Partners?		Calcium-dependent Cell-matrix Adhesion Magnesium Ion Transport Magnesium Ion Transmembrane Transporter Activity Programmed Necrotic Cell Death Magnesium Ion Homeostasis Magnesium Ion Transmembrane Transport Zinc Ion Transport Myosin Binding Intracellular Magnesium Ion Homeostasis Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Necroptotic Process Monoatomic Cation Channel Activity Protein Homotetramerization Calcium Channel Activity Protein Tetramerization Ruffle Cell-matrix Adhesion Actomyosin Structure Organization Protein Autophosphorylation Cell-substrate Adhesion Monoatomic Ion Channel Activity Cytoplasmic Vesicle Membrane Protein Homooligomerization Calcium Ion Transmembrane Transport Calcium Ion Transport Protein Complex Oligomerization
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