CPS1

Gene Name		carbamoyl-phosphate synthase 1, mitochondrial
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Gene Ontology Annotations	Cellular Component	Nucleolus Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Nucleoid Protein Complex
	Molecular Function	Carbamoyl-phosphate Synthase (ammonia) Activity Carbamoyl-phosphate Synthase (glutamine-hydrolyzing) Activity Endopeptidase Activity Calcium Ion Binding Protein Binding ATP Binding Phospholipid Binding Glutamate Binding Protein Complex Binding Modified Amino Acid Binding
	Biological Process	Urea Cycle Glycogen Catabolic Process Proteolysis Arginine Biosynthetic Process Glutamine Catabolic Process Midgut Development Response To Toxic Substance Response To Zinc Ion Response To Amine Citrulline Biosynthetic Process Triglyceride Catabolic Process Response To Food Response To Lipopolysaccharide Cellular Nitrogen Compound Metabolic Process Response To Drug Response To Starvation Response To Amino Acid Small Molecule Metabolic Process Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Vasodilation Nitric Oxide Metabolic Process Homocysteine Metabolic Process Anion Homeostasis Response To Growth Hormone Hepatocyte Differentiation Carbamoyl Phosphate Biosynthetic Process Cellular Response To CAMP Cellular Response To Glucagon Stimulus Cellular Response To Oleic Acid Response To Dexamethasone
Pathways		Urea cycle Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS		Body mass index (asthmatics) ( 23517042) Chronic kidney disease ( 20383146) Fibrinogen ( 20031577) Homocysteine levels ( 20154341) Metabolic traits ( 21886157) Metabolite levels ( 23378610) Non-small cell lung cancer ( 23144319)
Protein-protein Interactions		2 interactors: ARAF RAF1
Entrez ID		1373
HPRD ID		01995
Ensembl ID		ENSG00000021826
Uniprot IDs		B7ZAW0 P31327 Q6PEK7
PDB IDs		2YVQ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Peptidyl-serine Phosphorylation Death-inducing Signaling Complex Assembly Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Cellular Ketone Metabolic Process Regulation Of Proteolysis Positive Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Regulation Of Protein Phosphorylation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Cellular Protein Metabolic Process Activation Of Adenylate Cyclase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Adenylate Cyclase Activity Regulation Of Phosphorylation Protein Phosphorylation Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Regulation Of Apoptotic Process Positive Regulation Of Lyase Activity Regulation Of Phosphorus Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Cell Death Regulation Of Adenylate Cyclase Activity Regulation Of TOR Signaling Positive Regulation Of CAMP Biosynthetic Process Activation Of MAPKK Activity Regulation Of Cyclase Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of CAMP Metabolic Process Somatic Stem Cell Maintenance Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Protein Metabolic Process Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Protein Complex Assembly Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cellular Metabolic Process
Tagcloud ?		aberrations applying arid2 axin1 cdk15 creating deleterious disruptions drive driver fn1 fusions genomes hccs hnf4a integrations intronic mll4 recurrently rps6ka3 seq silent splice tert thrap3 transcriptomes transcriptomic tsc1 wgs